Fig. 2

Body weight changes over time for each experimental group. Body weight changes during period of HFD to induce obesity (a), during 8 weeks of exercise treatment (b), and during 8 weeks of detraining treatment (c). Values are presented mean ± SE. ND; Normal-diet + sedentary group, HF; High-fat diet + sedentary group, HFT; High-fat diet + Training group, HF-T; Training group after chronic HFD, HFT-DT; Detraining group after completion of regular exercise. ^** p < 0.01, ^*** p < 0.001; Significant difference between ND and HF group, ^# p < 0.05, ^## p < 0.01, ^### p < 0.001; Significant difference between HF and HFT group, ^† p < 0.05; Significant difference between HF and HFT-DT group. ^‡ p < 0.05; Significant difference between HF and HF-T group