Fig. 2
Time/dose response of Sch B treatment on serum apolipoprotein B48 (Apo B48) and very-low-density lipoprotein (VLDL) levels. Experimental details were described in Fig. 1. For the time course study, serum Apo 48 and VLDL levels were measured at 12, 24, 48, 72, 96, and 120 h after Sch B treatment (a and c). For the dose–response study, mice were intragastrically treated with Sch B (0.25–2 g/kg). Twenty-four h later, serum samples were obtained to determine the Apo B 48 and VLDL levels, as well as the E max, K D, and pD 2 values (b and d). Values given are the mean ± SEM, with n = 10. *P < 0.05, **P < 0.01 vs Control, using a one-way ANOVA followed by Dunnett’s multiple comparisons test, Student’s t-test or post-hoc analysis