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Table 2 Effects of SNPs on individuals’ serum lipid levels

From: SLC12A3 variants modulate LDL cholesterol levels in the Mongolian population

SNPs a Variables Genotypes/Mean (SD) ANOVA K-W
F p b Chi 2 p b
rs5803   TT(25) TC(126) CC(177)     
  TCHO 4.67 ± 1.80 5.21 ± 1.93 4.72 ± 1.93 2.591 0.076 6.536 0.038
  TG 1.59 ± 1.41 1.77 ± 1.48 1.72 ± 2.25 0.098 0.907 4.247 0.120
  HDL-c 1.49 ± 0.60 1.53 ± 0.57 1.42 ± 0.55 1.470 0.231 4.256 0.119
  LDL-c 3.10 ± 1.41 3.36 ± 1.38 2.93 ± 1.25 3.881 0.022 7.378 0.025
rs2010501   CC(16) CT(110) TT(195)     
  TCHO 4.07 ± 1.28 4.70 ± 1.97 5.12 ± 1.94 3.390 0.035 7.014 0.030
  TG 1.07 ± 0.66 1.64 ± 2.51 1.86 ± 1.62 1.492 0.227 13.604 0.001
  HDL-c 1.35 ± 0.54 1.45 ± 0.59 1.50 ± 0.56 0.620 0.538 1.690 0.430
  LDL-c 2.49 ± 0.86 2.87 ± 1.28 3.31 ± 1.37 5.868 0.003 11.173 0.004
rs711746   GG(48) GA(148) AA(125)     
  TCHO 4.14 ± 1.17 5.00 ± 2.01 5.14 ± 2.04 4.910 0.008 7.553 0.023
  TG 1.18 ± 0.48 1.83 ± 2.38 1.87 ± 1.61 2.444 0.088 11.284 0.004
  HDL-c 1.37 ± 0.48 1.49 ± 0.59 1.50 ± 0.57 1.020 0.362 2.177 0.337
  LDL-c 2.55 ± 0.85 3.10 ± 1.35 3.35 ± 1.42 6.333 0.002 9.911 0.007
  1. Abbreviation: TCHO total cholesterol (mmol/L), TG triglyceride (mmol/L), HDL-c high-density lipoprotein cholesterol (mmol/L), LDL-c low-density lipoprotein cholesterol (mmol/L), ANOVA one-way analysis of variance, K-W Kruskal-Wallis H test
  2. aSNPs, at least one positive association between individuals’ serum levels presented, were shown analyzed by both ANOVA and K-W tests
  3. bBold type denotes p < 0.05