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Table 2 Effects of SNPs on individuals’ serum lipid levels

From: SLC12A3 variants modulate LDL cholesterol levels in the Mongolian population

SNPs a

Variables

Genotypes/Mean (SD)

ANOVA

K-W

F

p b

Chi 2

p b

rs5803

 

TT(25)

TC(126)

CC(177)

    
 

TCHO

4.67 ± 1.80

5.21 ± 1.93

4.72 ± 1.93

2.591

0.076

6.536

0.038

 

TG

1.59 ± 1.41

1.77 ± 1.48

1.72 ± 2.25

0.098

0.907

4.247

0.120

 

HDL-c

1.49 ± 0.60

1.53 ± 0.57

1.42 ± 0.55

1.470

0.231

4.256

0.119

 

LDL-c

3.10 ± 1.41

3.36 ± 1.38

2.93 ± 1.25

3.881

0.022

7.378

0.025

rs2010501

 

CC(16)

CT(110)

TT(195)

    
 

TCHO

4.07 ± 1.28

4.70 ± 1.97

5.12 ± 1.94

3.390

0.035

7.014

0.030

 

TG

1.07 ± 0.66

1.64 ± 2.51

1.86 ± 1.62

1.492

0.227

13.604

0.001

 

HDL-c

1.35 ± 0.54

1.45 ± 0.59

1.50 ± 0.56

0.620

0.538

1.690

0.430

 

LDL-c

2.49 ± 0.86

2.87 ± 1.28

3.31 ± 1.37

5.868

0.003

11.173

0.004

rs711746

 

GG(48)

GA(148)

AA(125)

    
 

TCHO

4.14 ± 1.17

5.00 ± 2.01

5.14 ± 2.04

4.910

0.008

7.553

0.023

 

TG

1.18 ± 0.48

1.83 ± 2.38

1.87 ± 1.61

2.444

0.088

11.284

0.004

 

HDL-c

1.37 ± 0.48

1.49 ± 0.59

1.50 ± 0.57

1.020

0.362

2.177

0.337

 

LDL-c

2.55 ± 0.85

3.10 ± 1.35

3.35 ± 1.42

6.333

0.002

9.911

0.007

  1. Abbreviation: TCHO total cholesterol (mmol/L), TG triglyceride (mmol/L), HDL-c high-density lipoprotein cholesterol (mmol/L), LDL-c low-density lipoprotein cholesterol (mmol/L), ANOVA one-way analysis of variance, K-W Kruskal-Wallis H test
  2. aSNPs, at least one positive association between individuals’ serum levels presented, were shown analyzed by both ANOVA and K-W tests
  3. bBold type denotes p < 0.05