From: SLC12A3 variants modulate LDL cholesterol levels in the Mongolian population
SNPs a | Variables | Genotypes/Mean (SD) | ANOVA | K-W | ||||
---|---|---|---|---|---|---|---|---|
F | p b | Chi 2 | p b | |||||
rs5803 | TT(25) | TC(126) | CC(177) | |||||
TCHO | 4.67 ± 1.80 | 5.21 ± 1.93 | 4.72 ± 1.93 | 2.591 | 0.076 | 6.536 | 0.038 | |
TG | 1.59 ± 1.41 | 1.77 ± 1.48 | 1.72 ± 2.25 | 0.098 | 0.907 | 4.247 | 0.120 | |
HDL-c | 1.49 ± 0.60 | 1.53 ± 0.57 | 1.42 ± 0.55 | 1.470 | 0.231 | 4.256 | 0.119 | |
LDL-c | 3.10 ± 1.41 | 3.36 ± 1.38 | 2.93 ± 1.25 | 3.881 | 0.022 | 7.378 | 0.025 | |
rs2010501 | CC(16) | CT(110) | TT(195) | |||||
TCHO | 4.07 ± 1.28 | 4.70 ± 1.97 | 5.12 ± 1.94 | 3.390 | 0.035 | 7.014 | 0.030 | |
TG | 1.07 ± 0.66 | 1.64 ± 2.51 | 1.86 ± 1.62 | 1.492 | 0.227 | 13.604 | 0.001 | |
HDL-c | 1.35 ± 0.54 | 1.45 ± 0.59 | 1.50 ± 0.56 | 0.620 | 0.538 | 1.690 | 0.430 | |
LDL-c | 2.49 ± 0.86 | 2.87 ± 1.28 | 3.31 ± 1.37 | 5.868 | 0.003 | 11.173 | 0.004 | |
rs711746 | GG(48) | GA(148) | AA(125) | |||||
TCHO | 4.14 ± 1.17 | 5.00 ± 2.01 | 5.14 ± 2.04 | 4.910 | 0.008 | 7.553 | 0.023 | |
TG | 1.18 ± 0.48 | 1.83 ± 2.38 | 1.87 ± 1.61 | 2.444 | 0.088 | 11.284 | 0.004 | |
HDL-c | 1.37 ± 0.48 | 1.49 ± 0.59 | 1.50 ± 0.57 | 1.020 | 0.362 | 2.177 | 0.337 | |
LDL-c | 2.55 ± 0.85 | 3.10 ± 1.35 | 3.35 ± 1.42 | 6.333 | 0.002 | 9.911 | 0.007 |