Fatty acid
|
Group
|
Baseline
|
Week after start of treatment
|
---|
2
|
4
|
6
|
8
|
10
|
12
|
14
|
16
|
18
|
20
|
---|
Myristic C14:0
|
Control
|
0.18%
|
0.16%
|
0.18%
|
0.19%
|
0.16%
|
0.13%
|
0.17%
|
0.17%
|
0.16%
|
0.14%
|
0.17%
|
Treated
|
0.23%
|
0.22%
|
0.22%
|
0.19%
|
0.21%
|
0.21%
|
0.20%
|
0.15%
|
0.21%
|
0.19%
|
0.20%
|
Palmitic C16:0
|
Control
|
20.7%
|
21.0%
|
21.6%
|
21.7%
|
21.3%
|
20.8%
|
20.5%
|
20.6%
|
21.4%
|
20.3%
|
20.8%
|
Treated
|
21.9%
|
22.5%
|
22.7%
|
22.0%
|
22.5%
|
23.4%
|
21.9%
|
22.5%
|
22.3%
|
21.8%
|
21.4%
|
Palmitoleic C16:1n7
|
Control
|
0.15%
|
0.14%
|
0.16%
|
0.15%
|
0.14%
|
0.14%
|
0.15%
|
0.14%
|
0.13%
|
0.13%
|
0.13%
|
Treated
|
0.27%
|
0.28%
|
0.28%
|
0.22%
|
0.20%
|
0.15%
|
0.15%
|
0.19%
|
0.23%
|
0.22%
|
0.22%
|
Palmitelaidic C16:1n7t
|
Control
|
0.07%
|
0.07%
|
0.07%
|
0.07%
|
0.08%
|
0.06%
|
0.08%
|
0.07%
|
0.07%
|
0.06%
|
0.07%
|
Treated
|
0.12%
|
0.14%
|
0.14%
|
0.14%
|
0.15%
|
0.16%
|
0.17%
|
0.12%
|
0.13%
|
0.12%
|
0.12%
|
Stearic C18:0
|
Control
|
18.1%
|
18.1%
|
18.1%
|
18.3%
|
18.0%
|
17.6%
|
17.8%
|
18.1%
|
18.0%
|
17.8%
|
17.9%
|
Treated
|
15.9%
|
16.1%
|
16.0%
|
16.0%
|
16.4%
|
15.2%
|
15.7%
|
16.5%
|
16.2%
|
16.0%
|
16.0%
|
Oleic C18:1n9
|
Control
|
9.54%
|
9.49%
|
9.73%
|
9.72%
|
9.63%
|
9.50%
|
9.49%
|
9.59%
|
9.52%
|
9.30%
|
9.34%
|
Treated
|
10.4%
|
10.2%
|
9.98%
|
9.43%
|
9.45%
|
8.88%
|
9.14%
|
9.80%
|
9.73%
|
9.72%
|
9.46%
|
Elaidic C18:1n9t
|
Control
|
0.14%
|
0.13%
|
0.14%
|
0.15%
|
0.14%
|
0.15%
|
0.16%
|
0.17%
|
0.12%
|
0.12%
|
0.12%
|
Treated
|
0.14%
|
0.15%
|
0.15%
|
0.15%
|
0.17%
|
0.18%
|
0.17%
|
0.16%
|
0.14%
|
0.13%
|
0.12%
|
Linoleic C18:2n6
|
Control
|
22.7%
|
22.1%
|
22.7%
|
22.5%
|
22.4%
|
23.3%
|
23.4%
|
23.6%
|
24.8%
|
25.4%
|
25.4%
|
Treated
|
22.4%
|
20.3%
|
20.8%
|
19.0%
|
18.9%
|
16.7%
|
17.1%
|
21.2%
|
23.4%
|
23.9%
|
24.1%
|
Linoelaidic C18:2n6t
|
Control
|
0.30%
|
0.23%
|
0.25%
|
0.25%
|
0.19%
|
0.19%
|
0.18%
|
0.16%
|
0.17%
|
0.14%
|
0.17%
|
Treated
|
0.26%
|
0.21%
|
0.25%
|
0.16%
|
0.18%
|
0.15%
|
0.16%
|
0.15%
|
0.16%
|
0.14%
|
0.15%
|
alpha-linolenic C18:3n3
|
Control
|
0.20%
|
0.20%
|
0.26%
|
0.25%
|
0.27%
|
0.31%
|
0.31%
|
0.33%
|
0.38%
|
0.38%
|
0.38%
|
Treated
|
0.21%
|
0.22%
|
0.25%
|
0.22%
|
0.20%
|
0.18%
|
0.20%
|
0.28%
|
0.34%
|
0.35%
|
0.33%
|
gamma-linolenic C18:3n6
|
Control
|
0.10%
|
0.09%
|
0.09%
|
0.07%
|
0.10%
|
0.11%
|
0.10%
|
0.11%
|
0.10%
|
0.08%
|
0.09%
|
Treated
|
0.09%
|
0.09%
|
0.09%
|
0.07%
|
0.07%
|
0.04%
|
0.05%
|
0.06%
|
0.08%
|
0.07%
|
0.09%
|
Arachidic C20:0
|
Control
|
0.35%
|
0.35%
|
0.35%
|
0.35%
|
0.37%
|
0.35%
|
0.36%
|
0.37%
|
0.35%
|
0.37%
|
0.38%
|
Treated
|
0.32%
|
0.31%
|
0.33%
|
0.32%
|
0.34%
|
0.32%
|
0.32%
|
0.33%
|
0.34%
|
0.34%
|
0.37%
|
Eicosenoic C20:1n9
|
Control
|
0.52%
|
0.49%
|
0.51%
|
0.49%
|
0.50%
|
0.47%
|
0.45%
|
0.45%
|
0.44%
|
0.43%
|
0.45%
|
Treated
|
0.59%
|
0.55%
|
0.55%
|
0.51%
|
0.52%
|
0.44%
|
0.44%
|
0.46%
|
0.46%
|
0.45%
|
0.49%
|
Eicosadienoic C20:2n6
|
Control
|
0.79%
|
0.73%
|
0.70%
|
0.69%
|
0.68%
|
0.73%
|
0.73%
|
0.72%
|
0.75%
|
0.74%
|
0.74%
|
Treated
|
0.74%
|
0.72%
|
0.71%
|
0.64%
|
0.62%
|
0.55%
|
0.52%
|
0.69%
|
0.70%
|
0.72%
|
0.74%
|
Dihomo-g-linolenic C20:3n6
|
Control
|
1.27%
|
1.22%
|
1.23%
|
1.21%
|
1.13%
|
1.22%
|
1.23%
|
1.23%
|
1.20%
|
1.10%
|
1.12%
|
Treated
|
1.84%
|
1.61%
|
1.53%
|
1.15%
|
1.06%
|
0.81%
|
0.75%
|
1.12%
|
1.28%
|
1.36%
|
1.46%
|
Arachidonic C20:4n6
|
Control
|
13.9%
|
14.3%
|
13.4%
|
13.4%
|
13.7%
|
13.8%
|
13.9%
|
13.6%
|
12.8%
|
13.0%
|
12.6%
|
Treated
|
11.7%
|
11.9%
|
10.8%
|
10.5%
|
9.41%
|
8.49%
|
8.10%
|
8.63%
|
8.63%
|
9.53%
|
9.88%
|
Behenic C22:0
|
Control
|
0.40%
|
0.43%
|
0.36%
|
0.35%
|
0.45%
|
0.43%
|
0.41%
|
0.43%
|
0.36%
|
0.46%
|
0.40%
|
Treated
|
0.40%
|
0.38%
|
0.36%
|
0.42%
|
0.41%
|
0.37%
|
0.41%
|
0.38%
|
0.37%
|
0.39%
|
0.41%
|
Docosatetraenoic C22:4n6
|
Control
|
1.33%
|
1.33%
|
1.32%
|
1.31%
|
1.33%
|
1.34%
|
1.40%
|
1.36%
|
1.29%
|
1.30%
|
1.29%
|
Treated
|
1.39%
|
1.24%
|
1.11%
|
0.87%
|
0.70%
|
0.49%
|
0.39%
|
0.42%
|
0.47%
|
0.64%
|
0.74%
|
Docosapentaenoic C22:5n3
|
Control
|
2.10%
|
2.07%
|
2.09%
|
2.13%
|
2.13%
|
2.14%
|
2.12%
|
2.04%
|
1.95%
|
2.02%
|
2.06%
|
Treated
|
2.75%
|
3.18%
|
3.42%
|
3.93%
|
4.07%
|
4.36%
|
4.53%
|
4.16%
|
3.74%
|
3.65%
|
3.63%
|
Docosapentaenoic C22:5n6
|
Control
|
0.40%
|
0.54%
|
0.34%
|
0.36%
|
0.49%
|
0.48%
|
0.39%
|
0.41%
|
0.27%
|
0.42%
|
0.40%
|
Treated
|
0.41%
|
0.38%
|
0.30%
|
0.48%
|
0.43%
|
0.38%
|
0.39%
|
0.31%
|
0.29%
|
0.41%
|
0.46%
|
Lignoceric C24:0
|
Control
|
0.40%
|
0.46%
|
0.33%
|
0.30%
|
0.48%
|
0.47%
|
0.41%
|
0.39%
|
0.31%
|
0.46%
|
0.39%
|
Treated
|
0.39%
|
0.35%
|
0.32%
|
0.48%
|
0.44%
|
0.39%
|
0.44%
|
0.35%
|
0.32%
|
0.41%
|
0.44%
|
Nervonic C24:1n9
|
Control
|
0.41%
|
0.50%
|
0.30%
|
0.26%
|
0.48%
|
0.45%
|
0.39%
|
0.38%
|
0.25%
|
0.45%
|
0.33%
|
Treated
|
0.46%
|
0.44%
|
0.33%
|
0.58%
|
0.48%
|
0.40%
|
0.46%
|
0.33%
|
0.30%
|
0.42%
|
0.45%
|
Dose (mg phospholipids/kg bw/day)
|
50
|
150
|
450
|
0
|
Dose (mg [EPA/DHA]/kg bw/day)
|
9.35/5.48
|
28.0/16.4
|
84.1/49.3
|
0/0
|
- Doses of administered phospholipids and of EPA and DHA are shown at the end of the table