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Table 1 General and metabolic characteristics of the healthy subjects, patients with coronary artery disease (CAD), and patients with type 2 diabetes (Diabetes)

From: Method for estimating high sdLDL-C by measuring triglyceride and apolipoprotein B levels

 

Healthy subjects

CAD

Diabetes

Number

1665

528

201

Age, years

41 ± 12

67 ± 11a

61 ± 12a,b

Sex, M/F

954/711

414/114

125/76

Diabetes, n (%)

0

174 (33)

201 (100)

Total cholesterol, mg/dl

195.5 ± 33.5

197.1 ± 36.4

205.3 ± 49.6a,b

HDL-C, mg/dl

62.0 ± 15.3

47.2 ± 13.5a

48.2 ± 13.3a

TG, mg/dl

95.0 ± 65.2

131.5 ± 76.1a

142.0 ± 85.1a

LDL-C, mg/dl

113.9 ± 31.6

119.6 ± 32.4a

129.2 ± 40.4a,b

sdLDL-C, mg/dl

25.0 ± 13.0

35.3 ± 20.5a

40.3 ± 24.9a,b

lbLDL-C, mg/dl

88.9 ± 24.9

84.3 ± 29.1a

88.9 ± 31.7

Non-HDL-C, mg/dl

133.4 ± 33.7

149.9 ± 35.5a

157.1 ± 47.4a,b

sdLDL-C/LDL-C, %

21.6 ± 8.3

29.6 ± 15.0a

30.5 ± 14.5a

ApoB, mg/dl

88.3 ± 23.4

98.0 ± 23.6a

105.3 ± 31.4a,b

LDL-C/apoB

1.29 ± 0.12

1.22 ± 0.17a

1.23 ± 0.12a

LDL size, nm

26.1 ± 0.51

25.6 ± 0.41a

25.8 ± 0.50a,b

  1. Data are expressed as mean ± standard deviation
  2. Significance at p < 0.0001–0.05 by ANOVA
  3. CAD coronary artery disease, HDL-C high-density lipoprotein-cholesterol, TG triglyceride, LDL-C low-density lipoprotein-cholesterol, sdLDL-C small dense LDL-C, lbLDL-C large buoyant LDL-C, Non-HDL-C non high-density lipoprotein-cholesterol, Apo apolipoprotein
  4. avs. Healthy subjects; bvs. CAD