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Table 3 LDL window in 1665 healthy subjects

From: Method for estimating high sdLDL-C by measuring triglyceride and apolipoprotein B levels

 

“LDL window”

Groups

Normal

Hyper-TG

Hyper-apoB

Hyper-TG/-apoB

Number (M/F)

1261 (617/644)

100 (86/14)

196 (152/43)

108 (98/10)

%N/total N

75.7

6.0

11.8

6.5

Total cholesterol, mg/dl

185.4 ± 27.5

190.9 ± 23.0

239.9 ± 22.5a,b

236.3 ± 24.5a,b

HDL-C, mg/dl

64.7 ± 15.1

50.3 ± 12.0a

57.7 ± 13.1a,b

48.8 ± 10.0a,c

TG, mg/dl

72.3 ± 28.6

224.1 ± 89.7a

102.8 ± 26.7a,b

225.9 ± 93.2a,c

LDL-C, mg/dl

103.6 ± 23.9

108.1 ± 22.2

162.2 ± 19.0a,b

151.3 ± 25.2a,b,c

sdLDL-C, mg/dl

20.4 ± 8.9

31.2 ± 10.8a

37.2 ± 11.1a,b

49.2 ± 14.6a,b,c

lbLDL-C, mg/dl

83.1 ± 20.4

76.9 ± 20.4a

125.0 ± 19.5a,b

102.1 ± 23.5a,b,c

Non-HDL-C, mg/dl

120.6 ± 24.9

140.6 ± 19.8a

182.2 ± 16.8a,b

187.5 ± 23.3a,b

sdLDL-C/LDL-C, %

19.7 ± 7.0

29.3 ± 9.6a

23.0 ± 6.7a,b

32.8 ± 9.0a,b,c

ApoB, mg/dl

78.9 ± 16.0

93.9 ± 13.1a

122.6 ± 10.5a,b

128.8 ± 14.2a,b,c

LDL-C/apoB

1.30 ± 0.10

1.14 ± 0.16a

1.32 ± 0.09b

1.17 ± 0.12a,c

LDL size, nm

26.2 ± 0.41

25.5 ± 0.73a

25.8 ± 0.41a,b

25.4 ± 0.52a,c

Pattern B, n (%)*

81 (6.4)

46 (46)

55 (28.1)

61 (56.5)

sdLDL-C Q1, Q2, Q3, Q4, n

407, 391, 328, 135

6, 14, 27, 53

1, 8, 56, 131

1, 3, 6, 98

sdLDL-C Q1, Q2, Q3, Q4, %

32.3, 31.0, 26.0, 10.7

6.0, 14.0, 27.0, 53.0

0.5, 4.1, 28.6, 66.8

0.9, 2.8, 5.6, 90.7

  1. Data are expressed as mean ± standard deviation
  2. HDL-C high-density lipoprotein-cholesterol, TG triglycerides, LDL-C low-density lipoprotein-cholesterol, sdLDL-C small dense LDL-C, lbLDL-C large buoyant LDL-C, Non-HDL-C non high-density lipoprotein-cholesterol, Apo apolipoprotein, Pattern B LDL phenotype with an average diameter of <25.5 nm
  3. Significance at p < 0.0001–0.05 by ANOVA
  4. *Statistically significant differences
  5. avs. normal; bhyper-TG; cvs. hyper-apoB