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Table 4 LDL window in patients with type 2 diabetes

From: Method for estimating high sdLDL-C by measuring triglyceride and apolipoprotein B levels

  “LDL window”
Groups Normal Hyper-TG Hyper-apoB Hyper-TG/-apoB
Number (M/F) 105 (66/39) 19 (12/7) 38 (22/16) 39 (25/14)
%N/total N 52.2 9.5 18.9 19.4
Total cholesterol, mg/dl 176.0 ± 28.6 178.4 ± 24.8 241.7 ± 38.9a,b 261.4 ± 40.7a,b,c
HDL-C, mg/dl 49.3 ± 13.2 39.8 ± 7.9a 51.8 ± 14.5b 45.7 ± 12.6
TG, mg/dl 96.0 ± 26.5 198.4 ± 48.3a 118.0 ± 21.7b 261.3 ± 109.3a,b,c
LDL-C, mg/dl 105.6 ± 23.6 104.4 ± 20.6 168.9 ± 31.0a,b 165.8 ± 33.4a,b
sdLDL-C, mg/dl 26.4 ± 11.8 38.2 ± 17.2a 45.7 ± 18.9a 73.0 ± 27.1a,b,c
lbLDL-C, mg/dl 79.2 ± 20.1 66.1 ± 24.5 123.2 ± 34.7a,b 92.7 ± 31.8a,b,c
Non-HDL-C, mg/dl 126.7 ± 25.8 138.7 ± 22.5 189.9 ± 32.2a,b 215.7 ± 37.5a,b,c
sdLDL-C/LDL-C, % 24.9 ± 9.5 37.1 ± 15.8a 27.7 ± 13.0b 44.6 ± 15.8a,c
ApoB, mg/dl 84.6 ± 16.5 93.9 ± 13.8 128.4 ± 20.0a,b 143.7 ± 25.5a,b,c
LDL-C/apoB 1.24 ± 0.09 1.10 ± 0.12a 1.31 ± 0.09a,b 1.15 ± 0.13a,c
LDL size, nm 25.9 ± 0.44 25.6 ± 0.42 25.9 ± 0.49 25.4 ± 0.52a,c
Pattern B, n (%)* 18 (17.1) 6 (31.6) 11 (29.0) 24 (61.5)
sdLDL-C Q1, Q2, Q3, Q4, n 19, 21, 33, 32 1, 1, 6, 11 1, 3, 7, 27 0, 0, 3, 36
sdLDL-C Q1, Q2, Q3, Q4, % 18.1, 20.0, 31.4, 30.5 5.3, 5.3, 31.6, 57.9 2.6, 7.9, 18.4, 71.1 0, 0, 7.7, 92.3
  1. Data are expressed as mean ± standard deviation
  2. HDL-C high-density lipoprotein-cholesterol, TG triglycerides, LDL-C low-density lipoprotein-cholesterol, sdLDL-C small dense LDL-C, lbLDL-C large buoyant LDL-C, Non-HDL-C non high-density lipoprotein-cholesterol, Apo apolipoprotein, Pattern B LDL phenotype with an average diameter of <25.5 nm
  3. Significance at p < 0.0001–0.05 by ANOVA
  4. *Statistically significant differences
  5. avs. normal; bhyper-TG; cvs. hyper-apoB