Skip to main content

Table 4 LDL window in patients with type 2 diabetes

From: Method for estimating high sdLDL-C by measuring triglyceride and apolipoprotein B levels

 

“LDL window”

Groups

Normal

Hyper-TG

Hyper-apoB

Hyper-TG/-apoB

Number (M/F)

105 (66/39)

19 (12/7)

38 (22/16)

39 (25/14)

%N/total N

52.2

9.5

18.9

19.4

Total cholesterol, mg/dl

176.0 ± 28.6

178.4 ± 24.8

241.7 ± 38.9a,b

261.4 ± 40.7a,b,c

HDL-C, mg/dl

49.3 ± 13.2

39.8 ± 7.9a

51.8 ± 14.5b

45.7 ± 12.6

TG, mg/dl

96.0 ± 26.5

198.4 ± 48.3a

118.0 ± 21.7b

261.3 ± 109.3a,b,c

LDL-C, mg/dl

105.6 ± 23.6

104.4 ± 20.6

168.9 ± 31.0a,b

165.8 ± 33.4a,b

sdLDL-C, mg/dl

26.4 ± 11.8

38.2 ± 17.2a

45.7 ± 18.9a

73.0 ± 27.1a,b,c

lbLDL-C, mg/dl

79.2 ± 20.1

66.1 ± 24.5

123.2 ± 34.7a,b

92.7 ± 31.8a,b,c

Non-HDL-C, mg/dl

126.7 ± 25.8

138.7 ± 22.5

189.9 ± 32.2a,b

215.7 ± 37.5a,b,c

sdLDL-C/LDL-C, %

24.9 ± 9.5

37.1 ± 15.8a

27.7 ± 13.0b

44.6 ± 15.8a,c

ApoB, mg/dl

84.6 ± 16.5

93.9 ± 13.8

128.4 ± 20.0a,b

143.7 ± 25.5a,b,c

LDL-C/apoB

1.24 ± 0.09

1.10 ± 0.12a

1.31 ± 0.09a,b

1.15 ± 0.13a,c

LDL size, nm

25.9 ± 0.44

25.6 ± 0.42

25.9 ± 0.49

25.4 ± 0.52a,c

Pattern B, n (%)*

18 (17.1)

6 (31.6)

11 (29.0)

24 (61.5)

sdLDL-C Q1, Q2, Q3, Q4, n

19, 21, 33, 32

1, 1, 6, 11

1, 3, 7, 27

0, 0, 3, 36

sdLDL-C Q1, Q2, Q3, Q4, %

18.1, 20.0, 31.4, 30.5

5.3, 5.3, 31.6, 57.9

2.6, 7.9, 18.4, 71.1

0, 0, 7.7, 92.3

  1. Data are expressed as mean ± standard deviation
  2. HDL-C high-density lipoprotein-cholesterol, TG triglycerides, LDL-C low-density lipoprotein-cholesterol, sdLDL-C small dense LDL-C, lbLDL-C large buoyant LDL-C, Non-HDL-C non high-density lipoprotein-cholesterol, Apo apolipoprotein, Pattern B LDL phenotype with an average diameter of <25.5 nm
  3. Significance at p < 0.0001–0.05 by ANOVA
  4. *Statistically significant differences
  5. avs. normal; bhyper-TG; cvs. hyper-apoB