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Table 4 Mean TG and HDL-C levels according to genotypes

From: Common variants in the genes of triglyceride and HDL-C metabolism lack association with coronary artery disease in the Pakistani subjects

SNP

Genotype

TG(mmol/L)

HDL-C(mmol/L)

Mean TG

95% C.I

Mean HDL-C

95% C.I

rs328

GG

1.93 ± 0.14

1.7–2.1

1.8 ± 0.17

1.5–2

GC

2.2 ± 0.71

2–2.3

1.44 ± 0.47

1.3–1.5

CC

2.3 ± 0.8

2.3–2.4

1.36 ± 0.44

1.3–1.4

β (se)

0.16(0.08)

 

−0.11(0.05)

 

R2

0.2%

1.1%

p-value

0.06

0.02

rs662799

AA

2.27 ± 0.77

2.2–2.3

1.42 ± 0.45

1.4–1.5

AG

2.36 ± 0.83

2.2–2.5

1.28 ± 0.42

1.2–1.3

GG

2.56 ± 0.61

2.3–2.9

1.2 ± 0.41

1–1.4

β (se)

0.12(0.06)

 

−0.13(0.03)

 

R2

0.6%

0.8%

p-value

0.053

<0.0001

0.001

rs708272

TT

2.22 ± 0.7

2.1–2.3

1.5 ± 0.42

1.4–1.6

CT

2.3 ± 0.8

2.2–2.4

1.4 ± 0.5

1.3–1.4

CC

2.4 ± 0.8

2.3–2.5

1.3 ± 0.42–

1.2–1.3

β (se)

0.08(0.04)

 

0.1(0.03)

 

R2

0.1%

1.9%

p-value

0.08

<0.001

  1. β (Se) is per risk allele increase/decrease in lipid trait (Standard error)