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Table 3 Differentially expressed genes in the brain of HFD-fed mice

From: The effects of short-term high-fat feeding on exercise capacity: multi-tissue transcriptome changes by RNA sequencing analysis

Gene symbol Log2FC P- value Gene symbol Log2FC P- value Gene symbol Log2FC P- value
Alpi −3.65 0.022 Slc22a19 −3.40 0.008 Gm13986 −2.48 0.019
Alpk3 −6.59 0.009 Sly −6.59 0.009 Gm14302 −6.28 0.016
Bhlha15 −3.52 0.027 Smim24 −3.65 0.022 Gm14673 −2.43 0.018
Bmp8b −1.82 0.039 Spata18 −5.87 0.048 Gm14886 −6.02 0.033
Brs3 2.80 0.034 Tfap2a −2.26 0.033 Gm15174 −2.49 0.036
C6 −6.15 0.023 Tnfsf15 −5.87 0.048 Gm15302 −5.87 0.048
C87414 −5.87 0.048 Uncx −2.43 0.041 Gm15839 −1.96 0.047
Capn11 −2.98 0.010 Usp17la −1.86 0.039 Gm16028 −6.15 0.023
Ccr1 3.72 0.046 Vax2os −2.15 0.017 Gm16060 −5.87 0.048
Ccr4 −3.05 0.008 Zfp345 −2.89 0.032 Gm16513 −5.87 0.048
Cd200r3 −1.97 0.040 1700007P06Rik −6.02 0.033 Gm17085 −3.94 0.011
Cd274 −1.80 0.037 1700021A07Rik −3.38 0.042 Gm17535 −7.89 5.53E-09
Cd300lg −3.58 0.005 1700128F08Rik −2.23 0.012 Gm20505 −2.04 0.046
Ces5a −1.83 0.034 1810019N24Rik −6.02 0.033 Gm20663 −1.98 0.044
Cpa4 −5.87 0.048 2810404F17Rik −4.30 4.67E-04 Gm20831 −6.69 0.006
Csprs −3.38 0.042 3110067C02Rik −5.87 0.048 Gm21292 −3.39 0.003
Dsg3 −2.23 0.022 4931406B18Rik −1.69 0.050 Gm2165 −2.71 0.020
Egfros −6.39 0.016 9530056K15Rik −5.87 0.048 Gm21719 −6.15 0.023
Esp6 −6.86 0.005 C230088H06Rik −4.17 0.005 Gm21738 −6.61 2.23E-09
Ffar2 −3.38 0.042 C430042M11Rik −3.06 0.002 Gm21776 −6.69 0.006
Gcm1 −2.38 0.013 G430049J08Rik −2.29 0.025 Gm21784 −3.77 0.015
Hopxos −5.87 0.048 CH36-246D16.4 −3.02 0.009 Gm21989 6.03 0.048
Hoxd11 −3.61 3.48E-04 CH36-35H7.2 −7.54 0.001 Gm23897 −2.55 0.009
Insrr −2.45 0.010 CH36-399D20.1 −7.93 1.73E-04 Gm26573 −7.72 3.41E-04
Itgb6 −3.28 0.001 Gm10038 −2.16 0.026 Gm26583 −6.15 0.023
Klk14 −3.48 0.002 Gm10132 −6.02 0.033 Gm26648 −6.28 0.016
Lmx1b −3.02 0.003 Gm10134 −1.96 0.036 Gm26704 −5.05 9.17E-06
Lypd8 −4.17 0.005 Gm10172 −2.31 0.013 Gm26705 −2.22 0.017
Mep1b −2.76 0.020 Gm10715 −6.88 1.29E-09 Gm26719 −2.84 0.015
Mid1 −1.78 0.045 Gm10717 −6.11 3.59E-09 Gm26763 −6.15 0.023
Mpz −5.87 0.048 Gm10718 −6.15 2.98E-09 Gm26804 −7.01 0.003
Ms4a4b −7.01 0.003 Gm10719 −6.56 5.50E-10 Gm26857 −2.14 0.022
Muc19 −2.46 0.011 Gm10720 −4.94 1.06E-06 Gm26870 −6.03 4.96E-09
Muc6 −5.87 0.048 Gm10721 −8.04 1.26E-04 Gm27956 −6.39 0.016
Mylk4 −2.85 0.002 Gm10722 −5.19 7.91E-07 Gm3755 −1.96 0.036
Nkapl −2.72 0.046 Gm10800 −6.03 4.95E-09 RP23-184B11.4 −6.28 0.016
Nkx2-1 −3.40 2.13E-04 Gm10801 −5.91 8.73E-09 RP23-315H12.7 −5.87 0.048
Orly −6.69 0.006 Gm11168 −5.67 3.66E-08 RP23-458B6.16 −6.86 0.005
Otc 2.70 0.032 Gm11231 −2.18 0.032 RP23-91 L14.2 −6.59 0.009
Patl2 −5.87 0.048 Gm11398 −5.87 0.048 RP24-112B7.3 −3.24 0.012
Pcdh12 2.83 0.046 Gm11883 −5.87 0.048 RP24-209E1.3 −6.02 0.033
Pou1f1 −2.62 0.003 Gm11948 −5.87 0.048 RP24-228I22.1 −6.69 0.006
Pou2f2 −1.83 0.043 Gm12177 −2.43 0.021 RP24-319B23.2 −4.68 0.001
Pou2f3-rs1 −6.02 0.033 Gm12496 −2.91 0.013 RP24-369 J17.1 −6.39 0.016
Psg28 −1.83 0.042 Gm12652 −6.28 0.016 RP24-446E18.2 −6.02 0.033
Rbp2 −3.72 0.018 Gm13086 −2.34 0.023 RP24-482E11.1 −5.87 0.048
Rdh19 −6.28 0.016 Gm13465 −2.54 0.033 RP24-72B9.10 −6.02 0.033
Rhox8 −6.15 0.023 Gm13691 −6.28 0.016    
Serpina10 −4.52 0.002 Gm13961 −5.87 0.048    
  1. FC fold change