Fig. 1From: RETRACTED ARTICLE: Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidative stress and endoplasmic reticulum stressProgranulin treatment activated oxidative stress and ER stress, elevated autophagy and induced insulin insensitivity in adipocytes. a Protein expression of iNOS. b The relative protein quantity of iNOS. c Nitrate levels in the culture media. d Intracellular ROS levels. e Protein expression of CHOP and GRP78, and the phosphorylation of PERK. f The relative protein quantity of CHOP, GRP78 and p-PERK. g Protein expression of Atg7, p62 and LC3. h The relative protein quantity of Atg7, p62 and LC3. i IRS-1 tyrosine phosphorylation. j The relative protein quantity of IRS-1 tyrosine phosphorylation. k Glucose uptake. The relative quantity of proteins was analyzed using Quantity One software. A representative blot is shown and the data was expressed as mean ± SEM in each bar graph. *P < 0.05 (PGRN vs Control)Back to article page