Fig. 2

Systemic metabolic effects of dietary intervention (Return to NCD) and losartan (HF-HSD-LOS). a Progression of body weight (n = 9 per group). b Epididymal fat pad weight (n = 9 per group). c Intra-peritoneal glucose tolerance test (6 h fasting, 1 g/kg glucose) with associated area under the curve values, determined 2 weeks before sacrifice (n = 9 for HF-HSD and HF-HSD-LOS mice and n = 6 for NCD and Return to NCD mice). d HOMA-IR (fasting glucose (mg/dl) X fasting insulin (ng/ml)/405) at sacrifice (n = 8 per group). e Fasting plasma total cholesterol (n = 9 per group). Asterisks indicate significant difference versus HF-HSD mice. Data are presented as mean. Error bars are SEM