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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice

Fig. 4

Effect of dietary intervention (Return to NCD) and losartan (HF-HSD-LOS) on fibrogenesis and hepatic lipid metabolism. a mRNA levels of genes involved in fibrogenesis (Collagen type I alpha 1 (Col1a1), transforming growth factor β1 (TGF-β1) and tissue inhibitor of metalloproteinase 1 (Timp1)). b mRNA levels of genes involved in fatty acid transport (Fatty acid translocase/cluster of differentiation 36 (FAT/CD36), fatty acid transporter member 5 (FATP5)). c mRNA levels of genes involved in lipogenesis (Sterol regulatory element binding transcription factor 1 (SREBP1c), fatty acid synthase (FAS), acetyl-CoA carboxylase 1 (ACC1)). Asterisks indicate significant difference versus HF-HSD mice. N = 9 per group for all assays. Data are presented as mean. Error bars are SEM

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Lipids in Health and Disease

ISSN: 1476-511X