Table 1 Characteristics of included studies
From: Effects of simvastatin on serum adiponectin: a meta-analysis of randomized controlled trials
Author (year) | Design | Population | Number of subjects | Mean age | Male | Mean BMI | Dose | Duration | Adiponectin measurement |
|---|---|---|---|---|---|---|---|---|---|
Years | % | Kg/mb | mg/d | Weeks | |||||
Koh 2004 [13] | R, DB, PC, CO | HTN patients | 47 | 57.0 | 42.6 | 25.2 | 20 | 8 | ELISA |
Koh 2005 [14] | R, DB, PC, CO | T2DM patients | 50 | 59.0 | 60.0 | 25.5 | 20 | 8 | ELISA |
Devaraj 2007 [15] | R, DB, PC | MetS patients | 50 | 51.0 | 28.0 | 39.0 | 40 | 8 | RIA |
Pfutzner 2007 [16] | R, DB, PC | Non DM patients of increased CV risk | 84 | 58.9 | 36.9 | 31.3 | 40 | 12 | RIA |
Gouni-Berthold 2008 [17] | R | Healthy male | 48 | 31.4 | 100.0 | 25.4 | 40 | 2 | RIA |
Koh 2008–10 mga [18] | R, DB, PC | HC patients | 38 | 57.4 | 46.8 | 25.9 | 10 | 8 | ELISA |
Koh 2008–20 mga [18] | R, DB, PC | HC patients | 40 | 58.2 | 46.9 | 26.7 | 20 | 8 | ELISA |
Koh 2008–40 mga [18] | R, DB, PC | HC patients | 39 | 59.8 | 46.0 | 26.6 | 40 | 8 | ELISA |
Koh 2008–80 mga [18] | R, DB, PC | HC patients | 39 | 59.0 | 47.6 | 26.3 | 80 | 8 | ELISA |
Koh 2009 [20] | R, SB, PC | HC patients | 85 | 58.5 | 38.8 | 24.9 | 20 | 8 | ELISA |
Hu 2009 [19] | R | T2DM patients with carotid atherosclerosis | 43 | 57.0 | 53.5 | 24.3 | 40 | 12 | ELISA |
Koh 2011b-20 mgb [21] | R, SB, PC | HC patients | 67 | 57.7 | 46.1 | 24.4 | 20 | 8 | ELISA |
Koh 2011b-40 mgb [21] | R, SB, PC | HC patients | 67 | 59.7 | 44.9 | 24.5 | 40 | 8 | ELISA |
Moezzi 2014 [23] | R, DB, PC, CO | Patients of increased CV risk | 102 | 45.1 | 39.2 | 30 | 40 | 4 | ELISA |
Krysiak 2014 [22] | R, SB, PC | HC patients | 44 | 51.5 | 59 | 26.8 | 40 | 12 | ELISA |
Koh 2015 [24] | R, SB, PC | HC patients | 102 | 57 | 52.9 | 24.7 | 20 | 8 | ELISA |