Table 5 Fatty acid composition of heart phospholipids from control mice and high-fat diet (HFD) fed mice receiving hydroxytyrosol (HT) supplementation

C16:0

33.5 ± 2.9^c

32.8 ± 3.0^c

42.9 ± 3.4^a,b,d

34.7 ± 2.7^c

C18:0

4.84 ± 0.3

4.32 ± 0.5

3.94 ± 0.3

5.11 ± 0.5

C18:1n-9

22.8 ± 2.3

23.9 ± 2.5

22.4 ± 1.9

23.3 ± 2.7

C18:2n-6 (LA)

11.7 ± 1.5

11.6 ± 1.3

11.9 ± 1.6

12.5 ± 1.2

C18:3n-3 (ALA)

1.36 ± 0.1^c,d

1.44 ± 0.1^c,d

0.82 ± 0.04^a,b,d

1.12 ± 0.05^a,b,c

C20:4n-6 (AA)

11.6 ± 1.4

10.8 ± 1.2

10.90 ± 1.6

11.3 ± 1.7

C20:5n-3 (EPA)

2.82 ± 0.1^c,d

2.99 ± 0.1^c,d

0.98 ± 0.04^a,b,d

1.53 ± 0.05^a,b,c

C22:5n-6 (DPAn-6)

0.68 ± 0.1^c

0.75 ± 0.05^c

0.35 ± 0.02^a,b,d

0.62 ± 0.04^c

C22:5n-3 (DPAn-3)

0.72 ± 0.05^c

0.79 ± 0.1^c

0.28 ± 0.01^a,b,d

0.67 ± 0.05^c

C22:6n-3 (DHA)

5.15 ± 0.3^c

5.36 ± 0.2^c,d

2.05 ± 0.1^a,b,d

4.77 ± 0.2^b,c

Total SFAs

39.3 ± 3.3^c

37.8 ± 3.0^c

47.9 ± 4.1^a,b,d

40.3 ± 3.8^c

Total MUFAs

25.6 ± 2.6

26.9 ± 2.4

24.4 ± 2.2

25.6 ± 2.7

Total PUFAs

35.1 ± 3.1^c

35.3 ± 3.3^c

28.0 ± 2.5^a,b,d

34.1 ± 3.2^c

Total LCPUFAs

21.3 ± 1.8

21.0 ± 1.6

14.8 ± 0.5

19.9 ± 1.7

Total n-6 LCPUFAs

12.4 ± 1.2

11.7 ± 1.1

11.4 ± 0.9

12.4 ± 1.3

Total n-3 LCPUFAs

8.90 ± 0.5^c,d

9.30 ± 0.7^c,d

3.40 ± 0.2^a,b,d

7.50 ± 0.3^a,b,c

n-6/n-3 LCPUFA ratio

1.39 ± 0.2^c

1.26 ± 0.2^c

3.35 ± 0.2^a,b,d

1.65 ± 0.3^c