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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Hypercholesterolemia downregulates autophagy in the rat heart

Fig. 3

Hypercholesterolemia activated apoptosis, but had no effect on cardiac necroptosis. a Representative Western blots for apoptosis-related protein expressions. b-c Quantification of cleaved caspase-3 expression normalized to Actin and ratio of BCL-2 to BAX. d Representative Western blots for necroptosis-related proteins. e-g Quantification of RIP1, RIP3, MLKL and cleaved caspase-3 as normalized to Actin protein expression. NORM (n = 5) vs. CHOL (n = 5); mean + SEM; *: p < 0.05)

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