A Single Nucleotide Polymorphism in the FADS1 Gene is Associated with Plasma Fatty Acid and Lipid Profiles and Might Explain Gender Difference in Body Fat Distribution

Guo, Huilan; Zhang, Lichao; Zhu, Chaonan; Yang, Fei; Wang, Shanshan; Zhu, Shankuan; Ma, Xiaoguang

doi:10.1186/s12944-017-0459-9

Lipids in Health and Disease

Table 4 The association between rs174547 and fat distribution in men (N = 365)

From: A Single Nucleotide Polymorphism in the FADS1 Gene is Associated with Plasma Fatty Acid and Lipid Profiles and Might Explain Gender Difference in Body Fat Distribution

Indicators	T/T	T/C	C/C		P value^a		Effect (SD)	P value^b			Effect (SD)	P value^c
Indicators	Mean (SD)	Mean (SD)	Mean (SD)	Addictive	Dominant	Recessive	Effect (SD)	Addictive	Dominant	Recessive	Effect (SD)	Addictive	Dominant	Recessive
BMI (kg/m²)	23.53 (3.50)	23.71 (3.23)	23.70 (3.07)	0.889	0.689	0.822	-	-	-	-	-	-	-	-
Weight (kg)	66.36 (11.06)	66.69 (10.71)	65.91 (9.74)	0.861	0.925	0.670	−0.23 (0.35)	0.518	0.623	0.563	-	-	-	-
Waist circumference (cm)	86.17 (10.53)	85.45 (10.63)	86.02 (10.17)	0.561	0.565	0.719	−1.00 (0.50)	0.124	0.044*	0.704	-	-	-	-
Hip circumference (cm)	91.48 (10.50)	92.30 (6.01)	92.07 (5.24)	0.518	0.375	0.914	0.43 (0.65)	0.526	0.507	0.724	-	-	-	-
Waist-to-height ratio	0.51 (0.08)	0.51 (0.09)	0.52 (0.06)	0.962	0.844	0.882	−0.0006 (0.01)	0.977	0.929	0.958	-	-	-	-
Waist-to-hip ratio	0.93 (0.07)	0.93 (0.13)	0.93 (0.07)	0.509	0.767	0.404	−0.01 (0.01)	0.472	0.675	0.428	-	-	-	-
Android fat mass percent	2.54 (0.93)	2.48 (1.02)	2.54 (0.99)	0.593	0.601	0.736	−0.09 (0.06)	0.236	0.143	0.695	0.04 (0.06)	0.735	0.963	0.509
Gynoid fat mass percent	3.36 (0.98)	3.24 (1.00)	3.13 (1.01)	0.112	0.178	0.212	−0.14 (0.05)	0.010*	0.012*	0.098	−0.10 (0.04)	0.020*	0.040*	0.083
Android/gynoid fat ratio	0.75 (0.19)	0.75 (0.21)	0.80 (0.21)	0.447	0.758	0.318	0.03 (0.02)	0.328	0.719	0.183	-	-	-	-
Total fat mass percent	20.87 (7.19)	20.39 (7.72)	20.53 (7.69)	0.490	0.541	0.609	−0.85 (0.47)	0.111	0.071	0.474	-	-	-	-
Limb fat mass percent	6.9 (2.44)	6.70 (2.44)	6.58 (2.47)	0.287	0.364	0.405	−0.38 (0.18)	0.042*	0.033*	0.259	−0.15 (0.09)	0.089	0.108	0.253
Trunk fat mass percent	13.12 (4.89)	12.85 (5.35)	13.11 (5.26)	0.636	0.664	0.738	−0.45 (0.32)	0.254	0.164	0.693	0.13 (0.29)	0.824	0.974	0.664

^aAdujsted for age; ^bAdjusted for age, income, smoking, drinking, physical activity and BMI; ^cAdjusted for age, income, smoking, drinking, physical activity, B MI, and other regional fat (For android fat mass percent, the gynoid fat mass percent was further adjusted, vice versa; for limb fat mass percent, the trunk fat mass percent was further adjusted, vice versa); *P < 0.05

Back to article page

ISSN: 1476-511X

Contact us

General enquiries: journalsubmissions@springernature.com