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Table 6 Association between rs174547 and lipid profiles in men (N = 365)

From: A Single Nucleotide Polymorphism in the FADS1 Gene is Associated with Plasma Fatty Acid and Lipid Profiles and Might Explain Gender Difference in Body Fat Distribution

Indices

Effect (SD)

P valuea

Effect (SD)

P valueb

Effect (SD)

P valuec

Addictive

Dominant

Recessive

Addictive

Dominant

Recessive

Addictive

Dominant

Recessive

TG (mmol/l)

0.18 (0.35)

0.983

0.680

0.597

0.18 (0.09)

0.042*

0.112

0.079

0.21 (0.09)

0.021*

0.055

0.064

TC (mmol/l)

0.07 (0.13)

0.803

0.957

0.608

0.08 (0.13)

0.724

0.992

0.519

0.10 (0.13)

0.564

0.799

0.466

HDL-C (mmol/l)

0.02 (0.02)

0.252

0.399

0.292

0.04 (0.09)

0.789

0.997

0.628

0.07 (0.09)

0.499

0.663

0.488

LDL-C (mmol/l)

−0.04 (0.10)

0.858

0.953

0.695

−0.04 (0.04)

0.302

0.527

0.269

−0.03 (0.02)

0.128

0.266

0.159

Apoa1 (g/L)

0.02 (0.02)

0.437

0.530

0.517

0.02 (0.02)

0.356

0.418

0.485

0.01 (0.02)

0.646

0.726

0.683

Apob (g/L)

0.03 (0.03)

0.530

0.961

0.235

0.03 (0.02)

0.432

0.984

0.165

0.04 (0.03)

0.198

0.552

0.110

  1. aAdujsted for age; bAdjusted for age, income, smoking, drinking, physical activity and BMI; TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C high low-density lipoprotein cholesterol, Apoa1 Apolipoprotein A1, Apob Apolipoprotein B; cAdjusted for age, income, smoking, drinking, physical activity, BMI, and gynoid fat mass percent; *P < 0.05