Table 2 Changes in lipid parameters after intervention with oats
Per protocol | Intention-to-treata | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Variable | Control (n = 33) | Intervention (n = 36) | Control (n = 40) | Intervention (n = 40) | |||||
Mean ± SD | Mean ± SD | Difference (95% CI) | p value | Mean ± SD | Mean ± SD | Difference | p value | ||
LIPID PARAMETER | |||||||||
Total Cholesterol (mg/dL) | Baseline (n = 33) | 217.2 ± 11.4 | 217.3 ± 10.9 | - | 0.8 | 218.1 ± 11.9 | 217.1 ± 10.5 | - | 0.7 |
Post intervention | 208.7 ± 24.3 | 197.4 ± 21.7 | 11.3 (0.18, 22.3) | 0.04* | 210.9 ± 23.3 | 199.2 ± 21.2 | 11.8 (1.8, 21.7) | 0.02* | |
% Reduction | 4.0 ± 9.0 | 9.0 ± 9.7 | −5.0 (−9.5, −.5) | 0.03 | 3.3 ± 8.3 | 8.1 ± 9.6 | −4.8 (−8.8, −.8) | 0.01* | |
Low-Density Lipoprotein Cholesterol (mg/dL) | Baseline | 145.5 ± 17.7 | 144.4 ± 15.7 | - | 0.8 | 144.9 ± 16.4 | 145.1 ± 15.4 | - | 0.9 |
Post intervention | 137.5 ± 28.4 | 124.9 ± 20.2 | 12.5 (0.8, 24.3) | 0.04* | 138.4 ± 25.9 | 127.6 ± 21.0 | 10.8 0.29, 22.3) | 0.04* | |
% Reduction | 5.1 ± 17.9 | 12.9 ± 14.0 | −7.8 (−15.5, −.11) | 0.04* | 4.1 ± 16.3 | 11.6 ± 13.8 | −7.4(−14.1, −0.7) | 0.03* | |
Very Low-Density Lipoprotein Cholesterol (mg/dL) | Baseline | 31.5 ± 11.3 | 32.4 ± 11.9 | - | 0.8 | 32.4 ± 10.9 | 32.7 ± 12.5 | 0.9 | |
Post intervention | 34.1 ± 16.1 | 32.9 ± 13.4 | 1.2 (−5.9, 8.3) | 0.7 | 43.5 ± 15.1 | 33.2 ± 13.8 | 1.4 (−5.1, 7.8) | 0.7 | |
% Reduction | −21.8 ± 73.0 | −7.1 ± 39.9 | −14.7 (−42.7, 13.2) | 0.3 | −18.0 ± 66.7 | −6.3 ± 37.9 | −11.6 (−35.7, 12.5) | 0.3 | |
Serum Triglycerides (mg/dL) | Baseline | 157.6 ± 56.2 | 161.9 ± 59.4 | - | 0.8 | 162.2 ± 54.7 | 163.6 ± 62.5 | - | 0.9 |
Post intervention | 170.3 ± 80.6 | 164.4 ± 67.2 | 5.9 (−29.6, 41.5) | 0.7 | 172.7 ± 75.2 | 165.8 ± 69.2 | 6.8 (−25.3, 38.9) | 0.7 | |
% Reduction | −21.8 ± 73.0 | −7.1 ± 39.9 | −14.7 (−42.7, 13.2) | 0.3 | −18.0 ± 66.7 | −6.4 ± 37.9 | −11.6(−35.8, 12.5) | 0.34 | |
High-Density Lipoprotein Cholesterol (mg/dL) | Baseline | 39.1 ± 8.3 | 41.5 ± 12.5 | - | 0.4 | 39.6 ± 8.1 | 41.2 ± 12.1 | 0.5 | |
Post intervention | 37.1 ± 7.2 | 39.4 ± 9.5 | −2.4 (−6.5, 1.7) | 0.2 | 37.9 ± 7.3 | 39.3 ± 9.3 | −1.5 (−5.2, 2.3) | 0.4 | |
% Reduction | 3.8 ± 15.1 | 3.3 ± 14.1 | 0.5(−6.5, 7.5) | 0.9 | 3.1 ± 13.7 | 2.9 ± 13.3 | 0.2 (−5.8, 6.2) | 0.9 | |