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Table 2 Changes in lipid parameters after intervention with oats

From: Effects of 3 g of soluble fiber from oats on lipid levels of Asian Indians - a randomized controlled, parallel arm study

   Per protocol Intention-to-treata
Variable   Control (n = 33) Intervention (n = 36)    Control (n = 40) Intervention (n = 40)   
   Mean ± SD Mean ± SD Difference (95% CI) p value Mean ± SD Mean ± SD Difference p value
LIPID PARAMETER
Total Cholesterol (mg/dL) Baseline (n = 33) 217.2 ± 11.4 217.3 ± 10.9 - 0.8 218.1 ± 11.9 217.1 ± 10.5 - 0.7
Post intervention 208.7 ± 24.3 197.4 ± 21.7 11.3 (0.18, 22.3) 0.04* 210.9 ± 23.3 199.2 ± 21.2 11.8 (1.8, 21.7) 0.02*
% Reduction 4.0 ± 9.0 9.0 ± 9.7 −5.0 (−9.5, −.5) 0.03 3.3 ± 8.3 8.1 ± 9.6 −4.8 (−8.8, −.8) 0.01*
Low-Density Lipoprotein Cholesterol (mg/dL) Baseline 145.5 ± 17.7 144.4 ± 15.7 - 0.8 144.9 ± 16.4 145.1 ± 15.4 - 0.9
Post intervention 137.5 ± 28.4 124.9 ± 20.2 12.5 (0.8, 24.3) 0.04* 138.4 ± 25.9 127.6 ± 21.0 10.8 0.29, 22.3) 0.04*
% Reduction 5.1 ± 17.9 12.9 ± 14.0 −7.8 (−15.5, −.11) 0.04* 4.1 ± 16.3 11.6 ± 13.8 −7.4(−14.1, −0.7) 0.03*
Very Low-Density Lipoprotein Cholesterol (mg/dL) Baseline 31.5 ± 11.3 32.4 ± 11.9 - 0.8 32.4 ± 10.9 32.7 ± 12.5   0.9
Post intervention 34.1 ± 16.1 32.9 ± 13.4 1.2 (−5.9, 8.3) 0.7 43.5 ± 15.1 33.2 ± 13.8 1.4 (−5.1, 7.8) 0.7
% Reduction −21.8 ± 73.0 −7.1 ± 39.9 −14.7 (−42.7, 13.2) 0.3 −18.0 ± 66.7 −6.3 ± 37.9 −11.6 (−35.7, 12.5) 0.3
Serum Triglycerides (mg/dL) Baseline 157.6 ± 56.2 161.9 ± 59.4 - 0.8 162.2 ± 54.7 163.6 ± 62.5 - 0.9
Post intervention 170.3 ± 80.6 164.4 ± 67.2 5.9 (−29.6, 41.5) 0.7 172.7 ± 75.2 165.8 ± 69.2 6.8 (−25.3, 38.9) 0.7
% Reduction −21.8 ± 73.0 −7.1 ± 39.9 −14.7 (−42.7, 13.2) 0.3 −18.0 ± 66.7 −6.4 ± 37.9 −11.6(−35.8, 12.5) 0.34
High-Density Lipoprotein Cholesterol (mg/dL) Baseline 39.1 ± 8.3 41.5 ± 12.5 - 0.4 39.6 ± 8.1 41.2 ± 12.1   0.5
Post intervention 37.1 ± 7.2 39.4 ± 9.5 −2.4 (−6.5, 1.7) 0.2 37.9 ± 7.3 39.3 ± 9.3 −1.5 (−5.2, 2.3) 0.4
% Reduction 3.8 ± 15.1 3.3 ± 14.1 0.5(−6.5, 7.5) 0.9 3.1 ± 13.7 2.9 ± 13.3 0.2 (−5.8, 6.2) 0.9
  1. aSubjects who were not available post intervention, pre-intervention values were carried forward as post intervention values assuming that intervention did not have an effect on them
  2. *p < 0.05: statistically significant