Table 2 Association between groups with quartiles of biomarkers of inflammation, endothelial activation and oxidative stress
Biomarkers | FH | RUC | NC | p-value |
|---|---|---|---|---|
n (%) | n (%) | n (%) | ||
hsCRP (mg/L) | ||||
  < 0.30 | 19 (18.3) | 3 (7.5) | 22 (15.3) | 0.017 |
 0.30–0.69 | 15 (14.4) | 5 (12.5) | 39 (27.1) | |
 0.70–1.49 | 25 (24.0) | 11 (27.5) | 42 (29.2) | |
  ≥ 1.5 | 45 (43.3) | 21 (52.5) | 41 (28.5) | |
sICAM-1 (ng/ml) | ||||
  < 472 | 54 (45.8) | 3 (8.3) | 20 (13.0) | <0.001 |
 472–603 | 6 (5.1) | 4 (11.1) | 48 (31.2) | |
 604–772 | 7 (5.9) | 6 (16.6) | 50 (32.5) | |
  ≥ 773 | 51 (43.2) | 23 (63.9) | 36 (23.3) | |
E-selectin (ng/mL) | ||||
  < 16.53 | 8 (6.5) | 50 (100) | 65 (36.9) | <0.001 |
 16.5–26.0 | 8 (6.5) | 0 | 54 (30.2) | |
 26.1–101.7 | 29 (23.6) | 0 | 59 (33.0) | |
  ≥ 101.8 | 78 (63.4) | 0 | 0 | |
ox-LDL (mU/L) | ||||
  < 23.9 | 27 (24.1) | 38 (59.4) | 71 (39.0) | <0.001 |
 23.9–35.4 | 8 (7.1) | 5 (7.8) | 62 (34.1) | |
 35.5–53.7 | 26 (23.2) | 15 (23.4) | 43 (23.6) | |
  ≥ 53.8 | 51 (45.5) | 6 (9.4) | 6 (3.3) | |
MDA (nmol/mL) | ||||
  < 1.02 | 19 (22.1) | 6 (12.5) | 43 (27.4) | <0.001 |
 1.02–1.37 | 2 (2.3) | 5 (10.4) | 71 (45.2) | |
 1.38–2.33 | 11 (12.8) | 24 (50.0) | 43 (27.4) | |
  ≥ 2.34 | 54 (62.8) | 13 (27.1) | 0 (0.0) | |
F2- Isoprostanes (pg/L) | ||||
  < 1.04 | 0 (0.0) |  | 64 (42.1) | <0.001 |
 1.04–3.48 | 0 (0.0) |  | 47 (30.9) | |
 3.49–308 | 11 (21.6) |  | 41 (27.0) | |
  ≥ 309 | 40 (78.4) |  | 0 (0.0) | |