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Table 3 Independent predictors for endothelial activation and oxidative stress biomarkers in all subjects

From: Enhanced status of inflammation and endothelial activation in subjects with familial hypercholesterolaemia and their related unaffected family members: a case control study

Biomarkers Independent predictors Constant Beta SE Adjusted OR 95% CI (Lower boundary, Upper boundary) p-value
sICAM-1 FH -0.98 0.669 0.247 1.95 1.20, 3.17 0.007
RUC -1.42 1.871 0.398 6.50 2.98, 14.17 <0.001
Ox-LDL FH -0.75 1.621 0.248 35.1 3.11, 8.23 <0.001
MDA FH -2.49 3.56 0.39 5.06 16.4, 75.3 <0.001
  1. sICAM soluble intercellular adhesion molecule-1, MDA Malondialdehyde
  2. The model reasonably fits well. Model assumptions are met. There are no interaction and multicollinearity problem
  3. FH and RUC are independent predictors for sICAM after correcting for age, gender, ethnicity, HDL-c, diabetic, hypertension and smoking status
  4. FH is an independent predictor for oxLDL and MDA after correcting for age, gender, ethnicity, HDL-c, diabetic, hypertension and smoking status