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Table 3 Independent predictors for endothelial activation and oxidative stress biomarkers in all subjects

From: Enhanced status of inflammation and endothelial activation in subjects with familial hypercholesterolaemia and their related unaffected family members: a case control study

Biomarkers

Independent predictors

Constant

Beta

SE

Adjusted OR

95% CI (Lower boundary, Upper boundary)

p-value

sICAM-1

FH

-0.98

0.669

0.247

1.95

1.20, 3.17

0.007

RUC

-1.42

1.871

0.398

6.50

2.98, 14.17

<0.001

Ox-LDL

FH

-0.75

1.621

0.248

35.1

3.11, 8.23

<0.001

MDA

FH

-2.49

3.56

0.39

5.06

16.4, 75.3

<0.001

  1. sICAM soluble intercellular adhesion molecule-1, MDA Malondialdehyde
  2. The model reasonably fits well. Model assumptions are met. There are no interaction and multicollinearity problem
  3. FH and RUC are independent predictors for sICAM after correcting for age, gender, ethnicity, HDL-c, diabetic, hypertension and smoking status
  4. FH is an independent predictor for oxLDL and MDA after correcting for age, gender, ethnicity, HDL-c, diabetic, hypertension and smoking status