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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease

Fig. 2

Gene expression profiling by DNA microarray. Total RNA was extracted from 2 × 106 peripheral blood mononuclear cells (PBMCs) (n = 7). Differentially expressed genes > 2.0-fold change were further evaluated. (a) Heat maps of differentially expressed transcripts in PBMCs from hyperlipidaemia patients vs. control, and coronary heart disease (CHD) patients post-coronary bypass grafting vs. control. (b) Venn diagram illustrating the eight genes up-regulated in the two patient groups. (c) List of the eight genes common to both patient groups and their functions [7, 34, 35, 48–54]

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Lipids in Health and Disease

ISSN: 1476-511X