Fig. 2From: The omega-3 polyunsaturated fatty acid docosahexaenoic acid inhibits proliferation and progression of non-small cell lung cancer cells through the reactive oxygen species-mediated inactivation of the PI3K /Akt pathwayDHA induces the apoptosis in A549 cells. The rate of apoptotic cell death increased in the presence of 50 μM and 75 μM DHA (Fig. 2a and b). The level of the cleaved fragment of PARP slightly increased, whereas that of caspase3 was significantly elevated. The level of Bcl-2 decreased dramatically and that of Bax increased slightly (Fig. 2c )Back to article page