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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Genetic determinants of inherited susceptibility to hypercholesterolemia – a comprehensive literature review

Fig. 1

Schematic presentation of the pathways of cholesterol/lipoprotein metabolism and the genes involved. 7α-hydroxy cholesterol: 7α HC, Angiopoietin-like proteins: ANGPTL, Apolipoproteins: Apo., Cholesterol esters: CE, Cholesteryl ester transfer protein: CETP, Chylomicrons: CM, Endothelial lipase: EL, Fatty acids: FA, Free cholesterol: FC, Hepatic lipase: HL, High density lipoprotein: HDL, Inducible degrader of LDL receptor: IDOL, Intermediate-density lipoproteins: IDL, Lecithin: cholesterolacyl transferase: LCAT, Lipoprotein lipase: LPL, Lipoprotein-a: Lp(a), Low density lipoprotein: LDL, Lysosomal acid lipase: LAL, Scavenger receptor B1: SR-B1, Triglycerides: TG, Very low density lipoprotein: VLDL. Genes encoding lipoprotein receptors and receptor-related/associated proteins are in green colour. Genes encoding proteins with an enzymatic function in lipid/lipoprotein metabolism are in blue colour. Genes encoding lipid transporters and lipid transfer proteins are in brown colour. Genes encoding proteins with a regulatory function in lipid homeostasis are in purple colour

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Lipids in Health and Disease

ISSN: 1476-511X