Table 1 Candidate genes and SNP information
Gene | IS group (n = 408) | Control group (n = 347) | P |
|---|---|---|---|
Age (year-old) | 61.9 ± 11.8 | 61.8 ± 11.7 | 0.916 |
Sex (Male/Female, N) | 242/166 | 201/146 | 0.943 |
BMI (kg/m2) | 24.2 ± 3.3 | 23.9 ± 4.1 | 0.542 |
Hypertension (N, %) | 281(68.9) | 129(37.2) | <0.001 |
DM (N, %) | 129 (31.6) | 46(13.3) | <0.001 |
TC (mmol/L) | 4.85 ± 1.08 | 4.47 ± 1.01 | <0.001 |
TG (mmol/L) | 1.71 ± 0.65 | 1.51 ± 0.66 | <0.001 |
LDL-C (mmol/L) | 3.28 ± 0.61 | 2.46 ± 0.63 | <0.001 |
HDL-C (mmol/L) | 1.06 ± 0.25 | 1.27 ± 0.26 | <0.001 |
ApoA1 (g/L) | 0.83 ± 0.22 | 1.03 ± 0.31 | <0.001 |
ApoB (g/L) | 0.81 ± 0.22 | 0.95 ± 0.35 | <0.001 |
Lpa (mg/L) | 173.57 ± 53.17 | 123.81 ± 62.43 | <0.001 |