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Table 2 Mean plasma levels of n-3 and n-6 fatty acids in the FO group (n = 18) and MPL group (n = 15) at the beginning of the study (E1) and after 6 weeks (E2). All values are given in % of total fatty acids)

From: Dietary supplementation with n-3-fatty acids in patients with pancreatic cancer and cachexia: marine phospholipids versus fish oil - a randomized controlled double-blind trial

Fatty acid (mean)

E1

E2

P-value

change

EPA triglyceride

FO

0.55 ± 0.22

0.89 ± 0.31

0.001**

+62%

MPL

0.76 ± 0.51

1.05 ± 0.44

0.01**

+38%

EPA phospholipid*

FO

0.72 ± 0.31

1.16 ± 0.39

0.002**

+61%

MPL

1.08 ± 0.75

1.25 ± 0.53

0.20

+16%

EPA total*

FO

1.27 ± 0.51

2.05 ± 0.68

0.001**

+61%

MPL

1.83 ± 1.23

2.31 ± 0.91

0.034**

+55%

DHA triglyceride*

FO

0.71 ± 0.24

1.03 ± 0.36

<0.001**

+23%

MPL

0.94 ± 0.39

1.14 ± 0.30

0.003**

+14%

DHA phospholipid

FO

2.55 ± 0.73

3.46 ± 1.14

0.000**

+36%

MPL

3.14 ± 0.83

3.69 ± 0.70

0.005**

+18%

DHA total

FO

3.26 ± 0.84

4.49 ± 1.41

0.000**

+38%

MPL

4.07 ± 1.17

4.83 ± 0.96

0.004**

+19%

AA triglyceride

FO

4.43 ± 1.08

4.12 ± 1.02

0.09

-7%

MPL

4.24 ± 1.15

3.94 ± 0.99

0.296

-7%

AA phospholipid*

FO

9.07 ± 1.82

8.34 ± 1.45

0.05**

-8%

MPL

8.71 ± 1.37

8.51 ± 1.60

0.256

−2%

AA total

FO

13.5 ± 2.47

12.5 ± 2.27

0.027**

-7%

MPL

13.0 ± 2.02

12.4 ± 2.37

0.22

−5%

n:6/n:3 (total)

FO

3.13 ± 0.82

2.17 ± 1.11

<0.001**

-31%

MPL

2.44 ± 0.78

1.82 ± 0.49

0.000**

−25%

  1. *non- normally distributed, EPA eicosapentaenoic acid, DHA docosahexaenoic acid, AA arachidonic acid