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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Overexpression of apolipoprotein A-I alleviates endoplasmic reticulum stress in hepatocytes

Fig. 1

ApoA-I overexpression reduces TM-induced ER stress in HepG2 cells.HepG2 cells were transfected with pcDNA3.0 alone or with pcDNA3.0/apoA-I plasmid using the FuGENE HD transfection reagent. Twenty-four hours after transfection, the transfected cells were incubated for 24 h in DMEM in the presence or absence of 2 μg/mL TM, and total cellular proteins were isolated and analysed for apoA-I (a), GRP78 (b), CHOP (c) and P-PERK (d) by Western blotting. The results are representative of three independent experiments and are presented as the mean ± SEM. *P < 0.05 versus control. **P < 0.01 versus control. ***P < 0.001 versus control

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