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Table 3 Multivariate regression analysis showing independent contribution of FH status, BMI, PCSK9, gender and age on the variance of fasting plasma apolipoprotein B-48 concentrations

From: The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels

Independent variables

Partial (R2 X 100)

P

FH status

28.7

<0.0001

LDL-C levels

1.7

0.1

BMI

0.8

0.3

Sex

0.7

0.3

PCSK9 levels

0.4

0.4

Age

0.0

0.8

Total

32.3

<0.0001

  1. FH status refers to controls vs. HeFH vs. HoFH. FH familial hypercholesterolemia, BMI body mass index, PCSK9 proprotein convetase subtilisin/kexin type 9
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Lipids in Health and Disease

ISSN: 1476-511X