Effect of oral cinnamon intervention on metabolic profile and body composition of Asian Indians with metabolic syndrome: a randomized double -blind control trial

Table 2 Changes in body composition and blood pressure after 16 weeks of intervention

Body composition and blood pressure	Cinnamon group (n = 58)	Placebo group (n = 58)	Difference between Means (95% CI)	P value †
Weight (kg)^a
Baseline	89.1 ± 14.1	82.1 ± 14.1	7.0 (1.7, 12.1)	0.009*
16 weeks
Unadjusted	85.6 ± 13.7	81.7 ± 14.6	−3.9 (− 9.1, 1.3)	0.148
Adjusted	85.6 ± 13.7	81.7 ± 14.6	3.0 (−2.3, 3.8) ‡	0.001*
BMI (kg/m²)
Baseline	33.6 ± 5.4	31.2 ± 4.4	−2.4 (−0.5, − 4.2)	0.010*
16 weeks
Unadjusted	32.3 ± 5.2	31.0 ± 4.4	−1.3 (− 3.1, 0.5)	0.162
Adjusted	32.3 ± 5.2	31.0 ± 4.4	1.3 (0.9, 1.5) ‡	0.001*
WC (cm)
Baseline	106.6 ± 9.2	103.9 ± 9.3	−2.7 (−6.1, 0.7)	0.118
16 weeks
Unadjusted	101 ± 9.1	103.1 ± 9.7	2.2 (−1.3, 5.6)	0.223
Adjusted	101 ± 9.1	103.1 ± 9.7	4.8 (1.9, 7.7) ‡	0.002*
WHR
Baseline	0.94 ± 0.07	0.96 ± 0.08	0.02 (0.01, 0.04)	0.293
16 weeks
Unadjusted	0.91 ± 0.07	0.96 ± 0.08	0.05 (0.01, 0.06)	0.005*
Adjusted	0.91 ± 0.07	0.96 ± 0.08	0.03 (0.004, 0.06) ‡	0.028*
Body fat percentage
Baseline	37.9 ± 9.5	36.2 ± 8.4	- 1.7 (−5.1, 1.5)	0.295
16 weeks
Unadjusted	36.4 ± 9.5	36.2 ± 8.3	- 0.2 (−3.4,3.1)	0.928
Adjusted	36.4 ± 9.5	36.2 ± 8.3	3.0 (0.7, 5.3) ‡	0.011*
SBP (mmHg)
Baseline	135.8 ± 8.3	135.9 ± 8.6	−0.1 (− 3.1, 3.2)	0.939
16 weeks
Unadjusted	122.2 ± 6.3	130.5 ± 10.5	8.3 (5.1, 11.4)	0.001*
Adjusted	122.2 ± 6.3	130.5 ± 10.5	8.3 (5.0, 11.6) ‡	0.001*
DBP (mmHg)
Baseline	88.0 ± 6.1	88.1 ± 6.1	0.1 (− 2.1, 2.3)	0.938
16 weeks
Unadjusted	79.9 ± 5.7	86.9 ± 6.2	7.0 (4.8, 9.2)	0.001*
Adjusted	79.9 ± 5.7	86.9 ± 6.2	6.9 (4.6, 9.1) ‡	0.001*

BMI, body mass index; CI, confidence interval; DBP, diastolic blood pressure; SBP, systolic blood pressure; WC, waist circumference; WHR, waist hip ratio
^†Intervention vs. placebo
^‡Difference between placebo and cinnamon groups adjusted for BMI and a adjusted for baseline weight except weight using analysis of covariance
^§Values were presented as mean ± SD and median (min - max)
^* p value <0.05

ISSN: 1476-511X