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Table 3 Studies examining the effect of n-3 fatty acids as fish oils on CHD, stroke and total mortality

From: Docosahexaenoic acid regulates vascular endothelial cell function and prevents cardiovascular disease

Authors Results of meta-analyses of population studies
Wang et al. (2006) [76] ↓ all-cause mortality; cardiac and sudden death
Bucher et al. (2002) [73] ↓ total mortality; cardiac and sudden death
He et al. (2004) [77] ↓ CHD mortality
Whelton et al. (2004) [75] ↓ fatal and total CHD
He et al. (2004) [77] ↓ stroke, particularly ischaemic stroke
Xun et al. (2012) [78] ↓ stroke, particularly ischaemic stroke
Authors Results of randomised controlled trials
Burr et al. (1989) [79] ↓ all-cause mortality in post-MI patients
Valagussa et al. (1999) [80] ↓ total and cardiovascular mortality; sudden death in post-MI patients
Tavazzi et al. (2008) [82] ↓ total mortality and hospital admission for CVD in heart failure patients coronary events in patients with hypercholesterolaemia
Yokoyama et al. (2007) (81] cardiovascular events in patients at high risk of CVD and impaired glucose or diabetes
Bosch et al. (2012) [83] post-operative atrial fibrillation in patients undergoing cardiac surgery
Mozaffarian et al. (2012) [84] cardiovascular mortality and morbidity in patients with multiple cardiovascular risk factors
  1. Abbreviations: CHD coronary heart disease, CVD cardiovascular disease.
  2. Adapted from reference [62] Mori et al. 2014