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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: Advanced glycation end products (AGEs) increase renal lipid accumulation: a pathogenic factor of diabetic nephropathy (DN)

Fig. 6

Effects of AG on mRNA and protein expression of HMG-CoAR, LDLr, SREBP-2 and SCAP. The mRNA levels were determined for real-time RT-PCR as described in Materials and Methods. GAPDH served as a reference gene. Results represent the mean ± SD from 3 experiments (n = 6) (a). The protein levels were examined by Western blotting (b). The histogram represents mean ± SD of the densitometric scans for proteins from 3 experiments (n = 6), normalized by comparison with β-actin and expressed as a percentage of control (c). *P < 0.05, DM + AG vs. DM

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Lipids in Health and Disease

ISSN: 1476-511X