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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured mice

Fig. 4

PC and PE profiles in the plasma of APAP-treated mice. a The numbers of decreased and increased PCs/LPCs/PEs/LPEs in plasma upon APAP-treatment were summarized. We defined lipid species with statistically significant decrease or increase at least at one time-point among 1 h, 3 h and 6 h as the decreased or increased lipid species respectively. b and c 2 PCs (PC 33:1 and PC 34:3) and 4 PEs (PE 34:2, PE 36:3, PE 38:4 and PE 38:6) were increased significantly in APAP-treated group compared with saline-treated group at both 3 h and 6 h time points. The relative concentrations of these 6 phospholipids in plasma of APAP induced liver-injured mice at 0 h, 1 h, 3 h, 6 h, 12 h and 24 h time points were presented. d Pearson’s correlation was performed to analyze the correlation between these 6 phospholipid species and liver enzymes (ALT/AST). *statistically significant compared with saline-treated group

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Lipids in Health and Disease

ISSN: 1476-511X