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Table 1 Characteristics of the study subjects

From: Decreased circulating dihomo-gamma-linolenic acid levels are associated with total mortality in patients with acute cardiovascular disease and acute decompensated heart failure

 

Survivor group (n = 256)

Nonsurvivor group (n = 50)

p

Age (years)

64.7 ± 15.2

75.3 ± 10.7

<0.01

Male (n, %)

175 (68.4)

34 (68.0)

NS

Body mass index (kg/m2)

24.2 ± 4.5

22.1 ± 3.8

<0.01

Systolic blood pressure (mmHg)

134 ± 27

124 ± 32

0.03

Diastolic blood pressure (mmHg)

78 ± 19

70 ± 18

<0.01

Heart rate (/min)

85 ± 30

82 ± 25

NS

Ejection fraction (%)

51.6 ± 16.7

39.7 ± 20.1

<0.01

Diabetes mellitus (n, %)

86 (33.6)

21 (42.0)

NS

Dyslipidemia (n, %)

191 (74.6)

28 (56.0)

0.01

Hypertension (n, %)

174 (68.0)

34 (68.0%)

NS

Atrial fibrillation (n, %)

59 (23.1)

22 (44.0)

<0.01

Ischemic heart disease (n, %)

141 (55.1)

27 (54.0)

NS

Diagnosis

 Acute decompensated heart failure (n, %)

71 (27.7)

34 (68.0)

<0.01

 Acute coronary syndrome (n, %)

121 (47.3)

8 (16.0)

<0.01

Laboratory data

 Total cholesterol (mg/dL)

172 ± 38

153 ± 27

<0.01

 LDL-cholesterol (mg/dL)

105 ± 31

93 ± 21

0.03

 HDL- cholesterol (mg/dL)

44 ± 14

42 ± 12

NS

 Triglycerides (mg/dL)

116 ± 72

86 ± 39

0.01

 eGFR (mL/min/1.73m2)

71.9 ± 27.4

45.4 ± 26.8

<0.01

 Hemoglobin A1c (%)

6.2 ± 1.2

6.1 ± 0.8

NS

 Total protein (g/dL)

6.6 ± 0.6

6.5 ± 0.6

NS

 Albumin (g/dL)

3.8 ± 0.6

3.4 ± 0.5

<0.01

 Brain natriuretic peptide (pg/mL)

490 ± 762

1443 ± 1357

<0.01

Medication

 Diuretics (n, %)

45 (17.7)

29 (59.2)

<0.01

 Antiplatelets (n, %)

95 (37.4)

25 (51.0)

NS

 Anticoagulants (n, %)

39 (15.4)

22 (44.9)

<0.01

 ACE-I/ARBs (n, %)

111 (43.7)

29 (59.2)

NS

 β-blockers (n, %)

82 (32.3)

22 (44.9)

NS

 Calcium channel blockers (n, %)

94 (37.0)

18 (36.7)

NS

 Inotropic agents (n, %)

3 (1.2)

9 (18.4)

<0.01

 Statins (n, %)

81 (31.9)

16 (32.7)

NS

 Oral hypoglycemic agents (n, %)

45 (17.7)

9 (18.4)

NS

 Insulin (n, %)

15 (5.9)

3 (6.1)

NS

  1. Data are presented as mean ± standard deviation or number (percentage)
  2. LDL-cholesterol = low-density lipoprotein cholesterol, HDL-cholesterol = high-density lipoprotein cholesterol, eGFR = estimated glomerular filtration rate, ACE-I = angiotensin converting enzyme inhibitor, ARB = angiotensin-2 receptor blocker