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Table 1 Baseline clinical characteristics according to the statin use adherence at six months after discharge

From: Six-month adherence to Statin use and subsequent risk of major adverse cardiovascular events (MACE) in patients discharged with acute coronary syndromes

Baseline variables

Good adherence

Poor adherence

P-value

(n = 9019)

(n = 3497)

 

Studies, n(%)

 CPACS-1

1415(15.7)

512(14.6)

0.145

 CPACS-2

7604(84.3)

2985(85.4)

 

Male, n(%)

6380(70.7)

2390(68.3)

0.009

Age,mean(SD)

63.33(11.5)

63.34(11.8)

0.974

High School or higher, n(%)

3444(38.2)

1252(35.8)

0.013

Occupations, n(%)

 Employed

4605(51.1)

1767(50.5)

0.844

 Not-employed

4214(46.7)

1654(47.3)

 

 Unknown

200(2.2)

76(2.2)

 

Tertiary hospital, n(%)

5781(64.1)

1987(56.8)

<0.001

Having health insurance, n(%)

7308(81.0)

2700(77.2)

<0.001

Smoking, n(%)

2748(30.5)

1096(31.3)

0.343

Subtype of ACS, n(%)

 STEMI

3530(39.1)

1347(38.5)

0.104

 Non-STEMI

1206(13.4)

427(12.2)

 

 Unstable angina

4283(47.5)

1723(49.3)

 

CVD risk factors, n(%)

 Hypertension

6354(70.5)

2402(68.7)

0.053

 Diabetes Mellitus

1892(21.0)

655(18.7)

0.005

 Dyslipidemia*

4807(53.3)

1734(49.6)

<0.001

 Smoking

2748(30.5)

1096(31.3)

0.343

 Obesity

897(10.0)

321(9.2)

0.194

 Family history of early CHD, n(%)

414(4.6)

171(4.9)

0.476

Higher heart rate(> = 100/min),n(%)

657(7.3)

277(7.9)

0.224

Continuous ECG monitoring, n(%)

6487(71.9)

2436(69.7)

0.012

Treatments during hospitalization, n(%)

 PCI/CABG

4746(52.6)

1334(38.2)

<0.001

 Thrombolysis

608(6.7)

318(9.1)

<0.001

Statin before hospitalization

1681(18.6)

513(14.7)

<0.001

PCI/CABG in 0–6 months, n(%)

308(3.4)

131(3.8)

0.3663

Adherence of other medications in 0–6 months, n(%)

 Aspirin

8573(95.1)

2742(78.4)

<0.001

 Clopidogrel

5962(66.1)

1414(40.4)

<0.001

 Beta-blocker

6602(73.2)

1772(50.7)

<0.001

 Angiotensin-converting enzyme inhibitor/Angiotensin receptor blocker

6312(70.0)

1493(42.7)

<0.001

  1. *Dyslipidemia was defined as having a history of dyslipidemia or total serum cholesterol>=240mg/dL, or LDL-c>=160mg/dL, or triglyceride>=200mg/dL, or HDL-c<40mg/dL according to the guideline of China