Fig. 3From: Protective effects of orange (Citrus sinensis L.) peel aqueous extract and hesperidin on oxidative stress and peptic ulcer induced by alcohol in ratSubacute effect of Citrus sinensis peel extract (CSPE), Hesperidin (H) and Omeprazole (OM) on gene expression of COX-2 relative to β-actin in gastric mucosa of rats induced by ethanol (EtOH) in rats. Animals were pre-treated with various doses of CSPE (100, 200 and 400 mg/kg, b.w., p.o.), OM (20 mg/kg, b.w., p.o.), Hesperidin (50 mg/kg, b.w., p.o) or bi-distilled water, challenged with a single oral administration of EtOH (4 g/kg, b.w., p.o.) or NaCl 9‰ for two hours. The data are expressed as mean ± S.E.M. (n = 10)*: p < 0.05 compared to the control group and #: p < 0.05 compared to the EtOH groupBack to article page