Skip to main content

Table 2 Effect of Citrus sinensis peel extract (CSPE), Omeprazole (OM) and Hesperidin (H) on gastric macroscopic alterations induced by EtOH: ulcer index and Percentage of protection (%). Animals were pretreated with various doses of CSPE (100, 200 and 400 mg/kg, p.o.), OM (20 mg/kg, b.w., p.o.), H (50 mg/kg, p.o)

From: Protective effects of orange (Citrus sinensis L.) peel aqueous extract and hesperidin on oxidative stress and peptic ulcer induced by alcohol in rat

Pre-traitement

Stomach

 

Ulcer area (mm2)

(Mean ± S.E.M)

Percentage of protection (%)

Control

0

--

EtOH

98.50 ± 3.59*

--

EtOH + CSPE-100

71.60 ± 1.9**

27.26%

EtOH + CSPE-200

47.60 ± 1.88**

53.19%

EtOH + CSPE-400

11.20 ± 0.86**

89.80%

EtOH + Omeprazole

21.34 ± 1.72**

78.16%

EtOH + Hesperidin

26.42 ± 1.74**

73.60%

  1. The data are expressed as mean ± S.E.M. (n = 10) * p < 0.05 compared to control group and ** p < 0.05 compared to EtOH group