Table 5 C statistics and net reclassification improvement statistics of lipid parameters for major cardiovascular events in TNT and IDEAL
Models | C statistics | |
LDL cholesterol | 0.648 (0.634–0.662) | |
Non-HDL cholesterol | 0.650 (0.636–0.664) | |
Apolipoprotein B | 0.651 (0.637–0.665) | |
Estimated apoB | 0.650 (0.636–0.664) | |
Models | Net reclassification improvement statistics | P |
LDL cholesterol vs. apolipoprotein B | 3.5% (0.3–6.4) | 0.007 |
LDL cholesterol vs. estimated apoB | 3.2% (−0.3–6.4) | 0.09 |
LDL cholesterol vs. non-HDL cholesterol | 3.8% (0.5–6.8) | 0.013 |
Estimated apoB vs. non-HDL cholesterol | 5.2% (1.7–10.2) | 0.013 |
Estimated apoB vs. apolipoprotein B | 1.0% (−1.3–4.0) | 0.31 |
Non-HDL cholesterol vs. apolipoprotein B | 1.1% (−1.4–3.9) | 0.29 |