Table 1 Clinical and biochemical variables in controls and patients with NAFLD
Controls (n = 24) mean ± SD | Moderate NAFLD (n = 30) mean ± SD | Severe NAFLD (n = 47) mean ± SD | P value | |
|---|---|---|---|---|
Age | 50.8 ± 8.4 | 50.5 ± 10.6 | 50.5 ± 10.6 | 0.4 |
BMI | 30.9 ± 3.2 | 30.7 ± 2.9 | 32.3 ± 4.9 | 0.02 Controls vs Severe |
Azotemia | 21.5 ± 21.5 | 36.4 ± 10.2 | 34.6 ± 9.8 | 0.001 Controls vs Moderate and Severe |
Ferritin | 114.7 ± 148.6 | 137.9 ± 142.2 | 149.4 ± 178.9 | 0.42 |
ALT | 28.9 ± 20.4 | 29.2 ± 10.3 | 40.7 ± 23.0 | 0.02 Controls vs Severe |
AST | 21.91 ± 4.18 | 23.53 ± 4.91 | 29.37 ± 10.84 | 0.01 Controls vs Severe |
GGT | 29.9 ± 46.5 | 23.5 ± 12.1 | 31.9 ± 28.3 | 0.8 |
Total cholesterol | 198.6 ± 33.3 | 210.6 ± 33.9 | 208.6 ± 35.9 | 0.28 |
Cholesterol- HDL | 51.6 ± 13.2 | 48.1 ± 13.7 | 41.1 ± 8.3 | 0.001 Controls vs Severe |
Triglycerides | 100.7 ± 46.5 | 118.7 ± 69.1 | 151.2 ± 89.0 | 0.01 Controls vs Severe |
Glycemia | 87.4 ± 12.2 | 93.2 ± 6.0 | 98.8 ± 15.1 | 0.001 Controls vs Severe |
Serum Insulin | 7.18 ± 3.03 | 9.65 ± 3.96 | 13.2 ± 4.8 | 0.04 and 0.001 Controls vs Moderate and Severe, respectively |
HOMA index | 1.59 ± 0.72 | 2.22 ± 0.90 | 3.16 ± 1.27 | 0.04 and 0.001 Controls vs Moderate and Severe, respectively |
SFAs | 52.6 ± 8.8 | 52.3 ± 9.6 | 53.1 ± 10.9 | 0.84 |
MUFAs | 22.4 ± 5.5 | 22.6 ± 6.2 | 22.0 ± 7.2 | 0.8 |
PUFAs | 24.9 ± 5.7 | 25.0 ± 4.6 | 24.8 ± 5.6 | 0.9 |