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Table 2 Levels of IL-18, Leptin and Insulin in the three groups of animals during the entire experimental periodα

From: Per os colchicine administration in cholesterol fed rabbits: Triglycerides lowering effects without affecting atherosclerosis progress

 

Group

0 weeks

4 weeks

7 weeks

IL-18 (pg/mL)

ND

37.23 ± 31.87

80.49 ± 88.48

74.30 ± 104.17

CD

18.93 ± 14.29

45.35 ± 33.46a

42.72 ± 28.73a

CD + Col

52.37 ± 46.17

31.23 ± 20.09

38.49 ± 23.57

Leptin (ng/mL)

ND

7.63 ± 4.79

8.68 ± 3.50

10.80 ± 1.16

CD

7.12 ± 5.54

9.79 ± 0.48

10.27 ± 0.79b

CD + Col

7.61 ± 4.47

9.56 ± 0.95

10.89 ± 0.68a,b

Insulin (ng/mL)

ND

0.48 ± 0.26

0.34 ± 0.08

0.63 ± 0.2a,b

CD

0.55 ± 0.39

0.20 ± 0.04a

0.89 ± 0.4a,b

CD + Col

0.44 ± 0.33

0.86 ± 0.30a,c,d

0.86 ± 0.29a

  1. Paired samples Wilcoxon test adjusted with Benjamini-Hochberg procedure
  2. αData are presented as mean ± SD, a p < 0.05 vs. baseline, b p < 0.05 vs. 4 weeks, c p < 0.05 vs. ND group, d p < 0.05 vs. CD group – ND (n = 6), CD (n = 7), CD + Col (n = 10)