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Table 2 The genotypic and allelic frequencies between the case and control group

From: Interactions of six SNPs in APOA1 gene and types of obesity on low HDL-C disease in Xinjiang pastoral area of China

SNP

Genetype/Allelic

Control

Case

ORa

95%CI

P b

rs670

AA

12(1.4%)

16(3.8%)

1.00

  

AG

197(23.4%)

114(26.9)

2.62

1.059–6.465

0.037

GG

634(75.2%)

294(69.3)

1.38

1.004–1.886

0.047

G

1465(86.9%)

702(82.8%)

1.46

1.118–1.915

0.005

rs5069

CC

717(85.1)

364(85.8)

1.00

  

CT

126(14.9)

60(14.2%)

0.94

0.673–1.308

0.710

T

132(7.8%)

60(7.1%)

1.12

0.813–1.532

0.500

rs5072

CC

416(49.3%)

207(48.8%)

1.00

  

CT

356(42.2%)

187(44.1%)

1.06

0.828–1.346

0.660

TT

71(8.4%)

30(7.1%)

0.85

0.537–1.343

0.480

T

498(29.5%)

247(29.1%)

1.02

0.851–1.223

0.830

rs7116797

AA

118(14.0%)

49(11.6%)

1.00

  

AG

393(46.6%)

210(49.5%)

1.29

0.886–1.868

0.190

GG

332(39.4%)

165(38.9%)

1.20

0.817–1.753

0.360

G

1057(62.7%)

540(63.7%)

0.96

0.808–1.138

0.630

rs2070665

CC

416(49.3%)

207(48.8%)

1.00

  

CT

355(42.1%)

187(44.1%)

1.06

0.530–1.350

0.650

TT

72(8.5%)

30(7.1%)

0.84

0.530–1.323

0.450

T

499(29.6%)

247(29.1%)

1.02

0.853–1.226

0.810

rs1799837

AG

11(1.3%)

4(0.9%)

1.00

  

GG

832(98.7%)

420(99.1%)

1.39

0.439–4.386

0.580

G

1675(99.3%)

844(99.5%)

0.72

0.229–2.273

0.580

  1. rs670-AA, rs5069-CC and rs5072-CC genotypes used as a reference genotype for obtaining the odds ratio calculations separated for each single nucleotide polymorphism
  2. rs7116797-AA, rs2070665-CC and rs1799837-AG genotypes used as a reference genotype for obtaining the odds ratio calculations separated for each single nucleotide polymorphism
  3. a, bBinary logistical regression analysis was used to obtained P value, the odds ratio (OR) and 95% confidence interval (95% CI) to obtained the SNPs difference between case and control group with adjustments for nationalities, age and sex. P < 0.025 significant
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