Fig. 3

Salidroside pretreatment affects ABCA1 and LOX1 levels in ox-LDL–induced THP1 cells. (a) Protein expression of ABCA1 in salidroside-treated THP1 cells was analysed by western blotting. β-Actin was used as the control; (b) Quantification of ABCA1 protein expression in salidroside-treated THP1 cells; (c) Protein expression of ABCA1 in ox-LDL-treated THP1 cells was analysed by western blotting. β-Actin was used as the control; (d) Quantification of ABCA1 protein expression in ox-LDL–stimulated THP1 cells; (e) Salidroside treatment significantly decreased LOX1 expression in a dose-dependent manner; (f) Quantification of LOX1 protein expression in salidroside–incubated THP1 cells; (g) Ox-LDL incubation significantly increased LOX1 expression in a dose-dependent manner; (h) Quantification of LOX1 protein expression in the ox-LDL–stimulated THP1 cells; (i) to (k) ABCA1 protein expressions were restored and LOX1 protein expressions were reduced with salidroside treatment in a dose-dependent manner. Data are presented as mean ± standard deviation (SD). # p < 0.05 indicates significant difference from the control group. * p < 0.01 indicates significant difference from the control group