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Table 2 Genotype and allele frequencies of the BRCA2 rs9534275 SNP in cases and controls

From: Association between single nucleotide polymorphism rs9534275 and the risk of coronary artery disease and ischemic stroke

Genotype or allele Control [n (%)] CAD [n (%)] IS [n (%)] CAD IS
OR (95% CI) P OR (95% CI) P
TT 203 (31.4) 150 (24.8) 140 (24.6) 1   1  
GT 310(47.9) 316 (52.1) 291 (51.1) 1.58 (1.19–2.08) 0.365 1.52 (1.15–2.01) 0.214
GG 134 (20.7) 140 (23.1) 138 (24.3) 1.78 (0.82–1.91) 0.005 1.85 (1.32–2.59) 0.003
X 2   6.812 7.257     
P   0.033 0.027     
HWE (P) 0.349 0.33 0.62     
TT 203 (31.4) 150 (24.8) 140 (24.6) 1   1  
GT/GG 444 (68.6) 456 (75.2) 429 (75.4) 1.63 (1.25–2.12) 0.004 1.61 (1.24–2.10) 0.005
X 2   6.783 6.854     
P   0.01 0.009     
T 716 (55.3) 616 (50.8) 571 (50.2) 1   1  
G 578 (44.7) 596 (49.2) 567 (49.8) 1.35(1.14–1.60) 0.005 1.37 (1.16–1.62) 0.002
X 2   5.106 6.462     
P   0.025 0.012     
  1. Adjusted for sex, age, smoking, drinking, BMI, diabetes, hypertension, hyperlipidemia. CAD, coronary artery disease; IS, ischemic stroke