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Table 3 The risk of rs9534275 for CAD and IS according to body mass index (BMI), gender, smoking and drinking

From: Association between single nucleotide polymorphism rs9534275 and the risk of coronary artery disease and ischemic stroke

Factors Genetype CAD IS
OR (95% CI) P P interaction OR (95% CI) P P interaction
BMI
  < 24 Kg/m2 TT GT/GG 1   0.480 1   0.560
1.34(0.97–1.87) 0.078 1.36(0.97–1.87) 0.061
  ≥ 24 Kg/m2 TT 1   1  
GT/GG 1.47(0.98–2.20) 0.034 1.49(0.97–2.23) 0.047
Gender
 Male TT GT/GG 1   0.053 1   0.068
0.90(0.61–1.23) 0.681 0.97(0.73–1.34) 0.924
 Female TT 1   1  
GT/GG 4.20(2.56–4.69) 0.072 3.22(2.01–5.22) 0.064
Smoking
 Nonsmoker TT 1   0.350 1   0.160
GT/GG 1.38(0.98–1.94) 0.068 1.13(0.80–1.57) 0.492  
 Smoker TT 1   1  
GT/GG 1.48(1.03–2.14) 0.034 1.90(1.29–2.80) 0.001
Drinking
 Nondrinker TT 1   0.520 1   0.093
GT/GG 0.73(0.64–1.12) 0.335 0.87(0.68–3.73) 0.565
 Drinker TT 1   1  
GT/GG 0.81(0.66–1.28) 0.223 0.94(0.71–3.92) 0.324
  1. CAD, coronary artery disease; IS, ischemic stroke