Table 3 The risk of rs9534275 for CAD and IS according to body mass index (BMI), gender, smoking and drinking
Factors | Genetype | CAD | IS | ||||
|---|---|---|---|---|---|---|---|
OR (95% CI) | P | P interaction | OR (95% CI) | P | P interaction | ||
BMI | |||||||
  < 24 Kg/m2 | TT GT/GG | 1 |  | 0.480 | 1 |  | 0.560 |
1.34(0.97–1.87) | 0.078 | 1.36(0.97–1.87) | 0.061 | ||||
  ≥ 24 Kg/m2 | TT | 1 |  | 1 |  | ||
GT/GG | 1.47(0.98–2.20) | 0.034 | 1.49(0.97–2.23) | 0.047 | |||
Gender | |||||||
 Male | TT GT/GG | 1 |  | 0.053 | 1 |  | 0.068 |
0.90(0.61–1.23) | 0.681 | 0.97(0.73–1.34) | 0.924 | ||||
 Female | TT | 1 |  | 1 |  | ||
GT/GG | 4.20(2.56–4.69) | 0.072 | 3.22(2.01–5.22) | 0.064 | |||
Smoking | |||||||
 Nonsmoker | TT | 1 |  | 0.350 | 1 |  | 0.160 |
GT/GG | 1.38(0.98–1.94) | 0.068 | 1.13(0.80–1.57) | 0.492 |  | ||
 Smoker | TT | 1 |  | 1 |  | ||
GT/GG | 1.48(1.03–2.14) | 0.034 | 1.90(1.29–2.80) | 0.001 | |||
Drinking | |||||||
 Nondrinker | TT | 1 |  | 0.520 | 1 |  | 0.093 |
GT/GG | 0.73(0.64–1.12) | 0.335 | 0.87(0.68–3.73) | 0.565 | |||
 Drinker | TT | 1 |  | 1 |  | ||
GT/GG | 0.81(0.66–1.28) | 0.223 | 0.94(0.71–3.92) | 0.324 | |||