Skip to main content

Table 5 Association of the genotypes and serum lipid levels in controls and CAD and IS patients

From: Association between single nucleotide polymorphism rs9534275 and the risk of coronary artery disease and ischemic stroke

Genotype n TC (mmol/L) TG (mmol/L) HDL-C (mmol/L) LDL-C (mmol/L) ApoA1 (g/L) ApoB (g/L) ApoA1/ApoB
Control
 TT 203 4.58 ± 0.71 1.53 ± 2.38 1.90 ± 0.52 2.80 ± 0.75 1.43 ± 0.31 0.91 ± 0.22 1.65 ± 0.54
 GT 310 4.46 ± 0.50 1.37 ± 1.18 1.85 ± 0.42 2.74 ± 0.70 1.40 ± 0.23 0.90 ± 0.19 1.64 ± 0.51
 GG 134 4.48 ± 0.49 1.38 ± 1.70 1.98 ± 0.54 2.72 ± 0.62 1.42 ± 0.27 0.91 ± 0.26 1.64 ± 0.46
P   0.070 0.580 0.058 0.530 0.444 0.629 0.941
 TT 203 4.58 ± 0.71 1.53 ± 2.38 1.90 ± 0.52 2.80 ± 0.75 1.43 ± 0.31 0.91 ± 0.22 1.65 ± 0.54
 GT + GG 444 4.62 ± 0.49 1.47 ± 1.36 1.89 ± 0.46 2.75 ± 0.99 1.40 ± 0.25 0.92 ± 0.26 1.63 ± 0.49
P   0.072 0.297 0.786 0.278 0.283 0.374 0.729
CAD
 TT 150 4.55 ± 1.41 1.66 ± 1.09 1.13 ± 0.30 2.88 ± 0.75 1.07 ± 0.86 0.90 ± 0.27 1.23 ± 0.48
 GT 316 4.58 ± 2.78 1.70 ± 1.11 1.16 ± 0.34 2.92 ± 1.02 1.04 ± 0.38 1.63 ± 9.16 1.21 ± 0.52
 GG 140 4.61 ± 3.61 1.64 ± 1.03 1.16 ± 0.36 3.01 ± 1.33 1.03 ± 0.34 1.54 ± 4.43 1.17 ± 0.50
P   0.023 0.834 0.652 0.710 0.738 0.043 0.565
 TT 150 4.55 ± 1.41 1.66 ± 1.09 1.13 ± 0.30 2.88 ± 0.75 1.07 ± 0.86 0.90 ± 0.27 1.23 ± 0.48
 GT + GG 456 4.72 ± 6.38 1.78 ± 1.39 1.15 ± 0.34 2.95 ± 0.99 1.04 ± 0.37 1.62 ± 5.52 1.20 ± 0.51
P   0.018 0.810 0.356 0.887 0.443 0.031 0.548
IS
 TT 140 4.60 ± 1.46 1.90 ± 2.23 1.26 ± 0.54 2.90 ± 0.87 1.02 ± 0.24 0.99 ± 0.22 1.12 ± 0.56
 GT 291 4.52 ± 1.02 1.66 ± 1.22 1.21 ± 0.35 2.94 ± 0.83 1.03 ± 0.33 1.06 ± 0.19 1.09 ± 0.51
 GG 138 4.52 ± 1.07 1.62 ± 1.21 1.24 ± 0.33 2.93 ± 0.84 1.05 ± 0.22 1.03 ± 0.26 1.09 ± 0.46
P   0.777 0.232 0.456 0.930 0.896 0.789 0.713
 TT 140 4.60 ± 1.46 1.90 ± 2.23 1.26 ± 0.54 2.90 ± 0.87 1.02 ± 0.24 0.99 ± 0.22 1.12 ± 0.56
 GT + GG 337 4.58 ± 1.38 1.65 ± 1.39 1.22 ± 0.48 2.94 ± 0.99 1.06 ± 0.62 1.04 ± 0.26 1.09 ± 0.51
P   0.478 0.090 0.278 0.705 0.971 0.702 0.412
  1. Adjusted for sex, age, smoking, drinking, BMI, diabetes, hypertension, hyperlipidemia. TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B