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Table 5 Association of the genotypes and serum lipid levels in controls and CAD and IS patients

From: Association between single nucleotide polymorphism rs9534275 and the risk of coronary artery disease and ischemic stroke

Genotype

n

TC (mmol/L)

TG (mmol/L)

HDL-C (mmol/L)

LDL-C (mmol/L)

ApoA1 (g/L)

ApoB (g/L)

ApoA1/ApoB

Control

 TT

203

4.58 ± 0.71

1.53 ± 2.38

1.90 ± 0.52

2.80 ± 0.75

1.43 ± 0.31

0.91 ± 0.22

1.65 ± 0.54

 GT

310

4.46 ± 0.50

1.37 ± 1.18

1.85 ± 0.42

2.74 ± 0.70

1.40 ± 0.23

0.90 ± 0.19

1.64 ± 0.51

 GG

134

4.48 ± 0.49

1.38 ± 1.70

1.98 ± 0.54

2.72 ± 0.62

1.42 ± 0.27

0.91 ± 0.26

1.64 ± 0.46

  P

 

0.070

0.580

0.058

0.530

0.444

0.629

0.941

 TT

203

4.58 ± 0.71

1.53 ± 2.38

1.90 ± 0.52

2.80 ± 0.75

1.43 ± 0.31

0.91 ± 0.22

1.65 ± 0.54

 GT + GG

444

4.62 ± 0.49

1.47 ± 1.36

1.89 ± 0.46

2.75 ± 0.99

1.40 ± 0.25

0.92 ± 0.26

1.63 ± 0.49

  P

 

0.072

0.297

0.786

0.278

0.283

0.374

0.729

CAD

 TT

150

4.55 ± 1.41

1.66 ± 1.09

1.13 ± 0.30

2.88 ± 0.75

1.07 ± 0.86

0.90 ± 0.27

1.23 ± 0.48

 GT

316

4.58 ± 2.78

1.70 ± 1.11

1.16 ± 0.34

2.92 ± 1.02

1.04 ± 0.38

1.63 ± 9.16

1.21 ± 0.52

 GG

140

4.61 ± 3.61

1.64 ± 1.03

1.16 ± 0.36

3.01 ± 1.33

1.03 ± 0.34

1.54 ± 4.43

1.17 ± 0.50

  P

 

0.023

0.834

0.652

0.710

0.738

0.043

0.565

 TT

150

4.55 ± 1.41

1.66 ± 1.09

1.13 ± 0.30

2.88 ± 0.75

1.07 ± 0.86

0.90 ± 0.27

1.23 ± 0.48

 GT + GG

456

4.72 ± 6.38

1.78 ± 1.39

1.15 ± 0.34

2.95 ± 0.99

1.04 ± 0.37

1.62 ± 5.52

1.20 ± 0.51

  P

 

0.018

0.810

0.356

0.887

0.443

0.031

0.548

IS

 TT

140

4.60 ± 1.46

1.90 ± 2.23

1.26 ± 0.54

2.90 ± 0.87

1.02 ± 0.24

0.99 ± 0.22

1.12 ± 0.56

 GT

291

4.52 ± 1.02

1.66 ± 1.22

1.21 ± 0.35

2.94 ± 0.83

1.03 ± 0.33

1.06 ± 0.19

1.09 ± 0.51

 GG

138

4.52 ± 1.07

1.62 ± 1.21

1.24 ± 0.33

2.93 ± 0.84

1.05 ± 0.22

1.03 ± 0.26

1.09 ± 0.46

  P

 

0.777

0.232

0.456

0.930

0.896

0.789

0.713

 TT

140

4.60 ± 1.46

1.90 ± 2.23

1.26 ± 0.54

2.90 ± 0.87

1.02 ± 0.24

0.99 ± 0.22

1.12 ± 0.56

 GT + GG

337

4.58 ± 1.38

1.65 ± 1.39

1.22 ± 0.48

2.94 ± 0.99

1.06 ± 0.62

1.04 ± 0.26

1.09 ± 0.51

  P

 

0.478

0.090

0.278

0.705

0.971

0.702

0.412

  1. Adjusted for sex, age, smoking, drinking, BMI, diabetes, hypertension, hyperlipidemia. TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B
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Lipids in Health and Disease

ISSN: 1476-511X