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Table 3 Odd ratios (95% CI) for diabetes in hypertensive participants with elevated homocysteine levels according to quartiles of nontraditional lipid profiles

From: Relation of four nontraditional lipid profiles to diabetes in rural Chinese H-type hypertension population

Variables Lipid measures P for trend
  Quartile 1 Quartile 2 Quartile 3 Quartile 4
TG/HDL-C ratio ≤0.59 0.59–0.92 0.92–1.55 >1.55  
 Model 1 1.000 (reference) 1.094 (0.670–1.787) 2.552 (1.667–3.906) 4.604 (3.079–6.885) <0.001
 Model 2 1.000 (reference) 1.020 (0.623–1.670) 2.420 (1.578–3.711) 4.574 (3.054–6.852) <0.001
 Model 3 1.000 (reference) 0.955 (0.573–1.590) 2.044 (1.299–3.125) 3.275 (2.109–5.087) <0.001
TC/HDL-C ratio ≤3.12 3.12–3.80 3.80–4.58 >4.58  
 Model 1 1.000 (reference) 1.189 (0.757–1.868) 1.980 (1.310–2.993) 3.841 (2.619–5.634) <0.001
 Model 2 1.000 (reference) 1.161 (0.738–1.826) 1.882 (1.243–2.850) 3.673 (2.501–5.396) <0.001
 Model 3 1.000 (reference) 1.123 (0.702–1.797) 1.682 (1.079–2.621) 2.753 (1.783–4.252) <0.001
LDL-C/HDL-C ratio ≤1.64 1.64–2.11 2.11–2.65 >2.65  
 Model 1 1.000 (reference) 1.457 (0.948–2.239) 1.729 (1.141–2.618) 3.520 (2.403–5.156) <0.001
 Model 2 1.000 (reference) 1.424 (0.925–2.190) 1.648 (1.087–2.500) 3.363 (2.292–4.933) <0.001
 Model 3 1.000 (reference) 1.207 (0.769–1.894) 1.361 (0.874–2.120) 2.178 (1.415–3.351) <0.001
non-HDL-C ≤3.11 3.11–3.71 3.71–4.43 >4.43  
 Model 1 1.000 (reference) 1.203 (0.786–1.841) 1.830 (1.235–2.712) 2.832 (1.951–4.112) <0.001
 Model 2 1.000 (reference) 1.143 (0.745–1.751) 1.723 (1.160–2.559) 2.571 (1.761–3.755) <0.001
 Model 3 1.000 (reference) 0.902 (0.578–1.410) 1.315 (0.867–1.994) 1.648 (1.097–2.478) 0.002
  1. Model 1: unadjusted; Model 2: adjusted for age and sex; Model 3: adjusted for all the factors in Model 2 and race, education level, family income, current smoking and drinking status, physical activity, diet score, body mass index, waist circumference, systolic blood pressure, diastolic blood pressure, serum creatinine, history of stroke and cardiovascular disease (coronary heart disease, arrhythmia and heart failure), medication used
  2. Abbreviations: OR odd ratio, 95% CI 95% confidence interval, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, non-HDL-C, non-high-density lipoprotein cholesterol