Fig. 2From: Fenofibrate decreases the bone quality by down regulating Runx2 in high-fat-diet induced Type 2 diabetes mellitus mouse modelHFD-induced T2DM mice treated with fenofibrate showed low cortical porosity. Analysis of a cortical bone mineral density, b cortical thickness, and c cortical porosity of femur (n = 7). d Representative sections of femur from different groups were stained with TUNEL, and e apoptotic cells per field were counted from 5 slides (10 fields in each slide). f Bcl2 and g caspase 3 expression in MC3T3 cells treated with fenofibrate at different concentrations detected by qPCR. Results are presented as mean ± SD obtained from three repeated measurements. * P < 0.05, ** P < 0.01, *** P < 0.001Back to article page