Table 4 NLRP3, ASC, Caspase-1, IL-1 and IL-18 level in T2DM patients combined with CAS or not
Variables | T2DM, n = 26 | T2DM + AS, n = 81 | P |
|---|---|---|---|
NLRP3 mRNA, mean ± sd. | 1.74 ± 0.81 | 3.38 ± 1.74 | <0.001 |
ASC mRNA, mean ± sd. | 2.07 ± 0.92 | 2.48 ± 0.61 | 0.033 |
Caspase-1 mRNA, mean ± sd. | 2.86 ± 2.17 | 3.64 ± 1.80 | 0.065 |
IL-1β(pg/ml), mean ± sd. | 56.06 ± 36.97 | 54.87 ± 26.81 | 0.561 |
IL-18(pg/ml), mean ± sd. | 158.29 ± 88.96 | 149.2 ± 67.96 | 0.996 |