Table 5 NLRP3, ASC, Caspase-1, IL-1 and IL-18 level in T2DM + AS patients with plaque or not
Variables | IMT thicken, n = 32 | Plaque, n = 49 | P |
|---|---|---|---|
NLRP3 mRNA, mean ± sd. | 3.84 ± 1.51 | 2.95 ± 1.20 | 0.004 |
ASC mRNA, mean ± sd. | 2.76 ± 0.51 | 2.21 ± 0.39 | <0.001 |
Caspase-1 mRNA, mean ± sd. | 4.39 ± 1.63 | 2.94 ± 1.74 | <0.001 |
IL-1β(pg/ml), mean ± sd. | 60.48 ± 35.01 | 51.51 ± 20.19 | 0.682 |
IL-18(pg/ml), mean ± sd. | 186.57 ± 73.47 | 126.77 ± 53.88 | 0.003 |