Table 2 Clinical and laboratory characteristics of first-degree relatives (FDR) of patients with premature acute myocardial infarction and individuals with no family history of coronary artery disease (controls)
Parameters | FDR | Controls | p-valuea FDR vs control | ||
|---|---|---|---|---|---|
(n = 166) | (n = 111) | ||||
Female (n = 105) | Male (n = 61) | Female (n = 63) | Male (n = 48) | ||
Overweight n (%) | 78 (78) | 46 (80.7) | 43 (56.5) | 25 (71.4) | 0.051 |
Abdominal obesity n (%) | 92 (93.8) | 40 (71.4) | 66 (86.8) | 28 (80) | 0.976 |
Smoking n (%) | 29 (29.6) | 20 (32.7) | 1 (1.3) | 5 (14.2) | <0.001 |
Sedentarism | 105 (63.2) | 61 (36.7) | 63 (56.8) | 48 (43.2) | 1.000b |
Hypertension n (%) | 27 (25.7) | 15 (24.5) | 14.4 (11) | 40 (12) | 0.878 |
Diabetes n (%) | 15 (53.7) | 13 (46.4) | 1.3(1) | 3 (1) | <0.001 |
Prediabetes n (%) | 61.6 (40.4) | 23 (38.3) | 16 (21.0) | 10 (28.5) | 0.024 |
Dyslipidemia n (%) | 88 (62.8) | 52 (37.1) | 38 (50) | 29 (82.8) | <0.001 |
LDL-C > 160 mg/dL n (%) | 17 (16.5) | 6 (10.9) | 5 (6.5) | 3 (8.5) | 0.045 |
Low HDL-C n (%) | 87 (82.8) | 42 (68.8) | 35 (46) | 26 (74.2) | <0.001 |
TG >150 mg/dL n (%) | 42 (40) | 40 (65.5) | 16 (21) | 17 (48.5) | 0.003 |
Metabolic syndrome n (%) | 42 (40) | 29 (47.5) | 15 (19.7) | 14 (40) | <0.001 |