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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Apolipoprotein E gene polymorphism modifies fasting total cholesterol concentrations in response to replacement of dietary saturated with monounsaturated fatty acids in adults at moderate cardiovascular disease risk

Fig. 1

Mean (±SE) of changes in total cholesterol concentrations following three intervention diets [rich in either saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), and n-6 polyunsaturated fatty acids (PUFA)] according to the APOE SNP rs1064725 genotype (Pinteraction = 0.001). A general linear model analysis was performed with adjustments for age, sex, body mass index, and ethnicity. Individuals carrying the ‘TT’ genotype had lower total cholesterol levels after consuming the MUFA diet compared to the SFA or n-6 PUFA diets (Passociation = 0.004)

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