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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: ALA/LA ameliorates glucose toxicity on HK-2 cells by attenuating oxidative stress and apoptosis through the ROS/p38/TGF-β1 pathway

Fig. 2

Effects of ALA/LA on ROS level of HK-2 cells induced with high glucose (\( \overline{x} \) ±s). ROS generation of HK-2 cell treated with ALA/LA was evaluated by flow cytometery. Data are presented as mean ± SD. # P < 0.05 vs. control group. * P < 0.05, ** P < 0.01 vs. model group. N: normal control group; G: high glucose model group; A1-A4: ALA group at dose of 10, 50, 100, 200 μM; L1-L4:LA group at dose of 10, 50, 100, 200 μM; E1-E4 EPA group at dose of 10, 50, 100, 200 μM, M1-M3: mixture of ALA and LA group at dose of 50 μM with ALA/LA ratio of 1:1, 1:4, 1:8; M4-M6: mixture of ALA and LA group at dose of 100 μM with ALA/LA ratio of 1:1, 1:4, 1:8. a to f Effects of ALA, LA, EPA, ALA and LA with a different concentration on ROS generation of HK-2 cells induced with high glucose. g ROS level of HK-2 cell treated with ALA/LA (100 μM)

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